Full metadata record
DC Field | Value | Language |
---|---|---|
dc.contributor.author | Choe, Seungho | - |
dc.date.accessioned | 2023-07-17T10:10:19Z | - |
dc.date.available | 2023-07-17T10:10:19Z | - |
dc.date.created | 2023-07-17 | - |
dc.date.issued | 2023-02-21 | - |
dc.identifier.issn | 0006-3495 | - |
dc.identifier.uri | http://hdl.handle.net/20.500.11750/46199 | - |
dc.description.abstract | We report spontaneous translocation of a single cell-penetrating peptide (CPP) across a model membrane using the weighted ensemble (WE) method within the molecular dynamics (MD) simulations approach. Furthermore, we show that a water pore plays a crucial role in translocating the peptide and a tilt angle of the peptide also affects the translocation. Last, using umbrella sampling, we obtain the potential of mean force (PMF) along the translocation path and show that a single CPP's translocation is energetically unfavorable. | - |
dc.language | English | - |
dc.publisher | Biophysical Society | - |
dc.relation.ispartof | Biophysical journal | - |
dc.title | Translocation of cell-penetrating peptides using the weighted ensemble method within molecular dynamics simulations approach | - |
dc.type | Conference Paper | - |
dc.identifier.doi | 10.1016/j.bpj.2022.11.2045 | - |
dc.identifier.wosid | 000989629702058 | - |
dc.identifier.scopusid | 2-s2.0-85148075121 | - |
dc.identifier.bibliographicCitation | Biophysical Society Annual Meeting, pp.371a | - |
dc.identifier.url | https://www.biophysics.org/2023meeting/general-info | - |
dc.citation.conferenceDate | 2023-02-18 | - |
dc.citation.conferencePlace | US | - |
dc.citation.conferencePlace | San Diego | - |
dc.citation.startPage | 371a | - |
dc.citation.title | Biophysical Society Annual Meeting | - |
There are no files associated with this item.