Detail View

Multifaceted roles of CCAR family proteins in the DNA damage response and cancer
Citations

WEB OF SCIENCE

Citations

SCOPUS

Metadata Downloads

DC Field Value Language
dc.contributor.author Lugano, D. -
dc.contributor.author Barrett, L. -
dc.contributor.author Westerheide, S.D. -
dc.contributor.author Kee, Younghoon -
dc.date.accessioned 2024-02-21T09:40:16Z -
dc.date.available 2024-02-21T09:40:16Z -
dc.date.created 2024-01-11 -
dc.date.issued 2024-02 -
dc.identifier.issn 1226-3613 -
dc.identifier.uri http://hdl.handle.net/20.500.11750/47969 -
dc.description.abstract The cell cycle apoptosis regulator (CCAR) family of proteins consists of two proteins, CCAR1 and CCAR2, that play a variety of roles in cellular physiology and pathology. These multidomain proteins are able to perform multiple interactions and functions, playing roles in processes such as stress responses, metabolism, and the DNA damage response. The evolutionary conservation of CCAR family proteins allows their study in model organisms such as Caenorhabditis elegans, where a role for CCAR in aging was revealed. This review particularly highlights the multifaceted roles of CCAR family proteins and their implications in the DNA damage response and in cancer biology. © 2023, The Author(s). -
dc.language English -
dc.publisher Springer Nature -
dc.title Multifaceted roles of CCAR family proteins in the DNA damage response and cancer -
dc.type Article -
dc.identifier.doi 10.1038/s12276-023-01139-1 -
dc.identifier.wosid 001135877200006 -
dc.identifier.scopusid 2-s2.0-85181231009 -
dc.identifier.bibliographicCitation Experimental & Molecular Medicine, v.56, no.1, pp.59 - 65 -
dc.identifier.kciid ART003048383 -
dc.description.isOpenAccess TRUE -
dc.subject.keywordPlus TUMOR-SUPPRESSOR -
dc.subject.keywordPlus DBC1 -
dc.subject.keywordPlus BINDING -
dc.subject.keywordPlus COMPLEX -
dc.subject.keywordPlus INHIBITION -
dc.subject.keywordPlus ACTIVATION -
dc.subject.keywordPlus APOPTOSIS-REGULATORY PROTEIN-1 -
dc.subject.keywordPlus DOUBLE-STRAND BREAKS -
dc.subject.keywordPlus CELL-CYCLE -
dc.subject.keywordPlus SIRT1 DEACETYLASE -
dc.citation.endPage 65 -
dc.citation.number 1 -
dc.citation.startPage 59 -
dc.citation.title Experimental & Molecular Medicine -
dc.citation.volume 56 -
dc.description.journalRegisteredClass scie -
dc.description.journalRegisteredClass scopus -
dc.description.journalRegisteredClass kci -
dc.relation.journalResearchArea Biochemistry & Molecular Biology; Research & Experimental Medicine -
dc.relation.journalWebOfScienceCategory Biochemistry & Molecular Biology; Medicine, Research & Experimental -
dc.type.docType Review -
Show Simple Item Record

File Downloads

  • There are no files associated with this item.

공유

qrcode
공유하기

Related Researcher

기영훈
Kee, Younghoon기영훈

Department of New Biology

read more

Total Views & Downloads