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Determining the biophysical properties of indolicidin-derived antimicrobial peptide

Title
Determining the biophysical properties of indolicidin-derived antimicrobial peptide
Alternative Title
인돌리시딘 유래 항균 펩타이드의 생물물리학적 특성에 대한 연구
Author(s)
Jihyun Kim
DGIST Authors
Jihyun KimChang Hoon NamJin Hae Kim
Advisor
남창훈
Co-Advisor(s)
Jin Hae Kim
Issued Date
2024
Awarded Date
2024-02-01
Type
Thesis
Description
Antimicrobial peptide;Amphipathicity;Structural rigidity;Membrane selectivity;Mode of action
Table Of Contents
Ⅰ. Introduction 1
Ⅱ. Materials and methods 2
2.1 Peptide synthesis 2
2.2 Optical Diffraction Tomography (ODT) assay 3
2.3 Nuclear Magnetic Resonance (NMR) 3
2.4 Simulation 6
Ⅲ. Results 7
3.1 Tomographic analysis of E. coli 7
3.2 Tomographic analysis of sRBCs 7
3.3 NMR Experiments and Structural Model Calculation 11
3.4 Simulation 15
Ⅳ. Discussion 20
References 23
URI
http://hdl.handle.net/20.500.11750/48062

http://dgist.dcollection.net/common/orgView/200000725083
DOI
10.22677/THESIS.200000725083
Degree
Master
Department
Department of New Biology
Publisher
DGIST
Related Researcher
  • 남창훈 Nam, Chang-Hoon
  • Research Interests Protein Engineering; History and Philosophy of Science; Scientific Art; Biomaterial Development (Tissue Engineering) with modified bacteriophage; Bio Sensor Development
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Department of New Biology Theses Master

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