Mixed-spinel magnesioferrite MgFe2O4 basedElectrochemical Sensor

Abstract

Ascorbic acid (AA) or vitamin C is an effective antioxidant and reducing agent which plays a significant role in essential enzymatic reactions and precluding radical-induced disorders. The standard AA concentration in the human body ranges between 0.6 and 2 mg dL−1 , and many diseases are associated with AA concentration changes [1]. Its deficiency leads to scurvy, rheumatoid arthritis, Parkinson's disease, and even cancer, whereas excessive intake of AA causes impaired kidney functions and stomach irritation. Therefore, AA's quantitative and accurate determination is crucial for healthcare [2]. AA electrochemical detection can be performed in two possible ways, (i) enzymatic and (ii) non-enzymatic [3]. Among these two, the enzymatic sensors have major disadvantages due to the high cost, limited working conditions, and lack of reproducibility. On the other hand, non-enzymatic detection holds significance due to its stability and high sensitivity. Furthermore, these electrochemical techniques often suffer in real-time applications due to their low selectivity and sensitivity when using bare electrodes. Among several spinel ferrites, MgFe2O4 is of particular interest, which in the bulk state shows ferrimagnetism and crystallizes in a cubic structure. It is reported to have a minimal cytotoxic effect, ease of fabrication, cost-effectiveness, superior chemical stability, high capacity, and biocompatibility, making this ferrite an excellent candidate for electrochemical sensing.