Title

Site-specific Fabrication of Photo-responsive Melanin-mimetic Pigments

DGIST Authors

Haejin Jeong ; Seonki Hong ; Jinhee Park

Advisor

홍선기

Co-Advisor(s)

Jinhee Park

Issued Date

2024

Awarded Date

2024-08-01

Citation

Haejin Jeong. (2024). Site-specific Fabrication of Photo-responsive Melanin-mimetic Pigments. doi: 10.22677/THESIS.200000805381

Type

Thesis

Description

Melanin, Catecholamine, Pigmentation, Site-specific fabrication, Photoresponsive materials

Table Of Contents

Chapter I. Background 1
1.1. Polydopamine as a synthetic melanin analogue 1
1.2. Versatile adhesive properties of polydopamine 2
1.3. Complexity in polydopamine formation pathway 3

Chapter IⅠ. Spatially Controlled Coating Growth at Solid/Water Interface: Site-specific Fabrication of Melanin-like Pigments Underwater Adhesive Properties 5
2.1. Introduction 5
2.2. Results 9
2.2.1. Solution-phase screening of precursor candidates for melanin-like pigment generation mediated by HRP 9
2.2.2. The precursor-dependent behavior of surface-initiated pigment generation through PAINT 15
2.2.3. Incorporation of amine-containing additives during PC-based PAINT 21
2.2.4. Photothermal conversion activity of melanin-like pigment fabricated by PAINT
for biomedical applications 30
2.3. Discussion 35
2.4. Experimental section 36
2.4.1. Materials 36
2.4.2. HRP-mediated pigmentation in solution 36
2.4.3. Pigmentation on the surface through the PAINT method 36
2.4.4. HRP activity monitoring 37
2.4.5. Characterization 37
2.4.6. Biocompatibility test and photothermal ablation of cells seeded on pigment 38
2.4.7. NIR-derived actuation of Janus-faced hydrogel 38

References 40
Summary 47

URI

http://hdl.handle.net/20.500.11750/57593
http://dgist.dcollection.net/common/orgView/200000805381

DOI

10.22677/THESIS.200000805381

Degree

Doctor

Department

Department of Physics and Chemistry

Publisher

DGIST

Show Full Item Record