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Extra-nasal odorant receptors regulate the progression of glioblastoma
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Title
Extra-nasal odorant receptors regulate the progression of glioblastoma
Alternative Title
비강 외 후각 수용체들의 교모세포종 진행 조절
DGIST Authors
Jae Won HwangJaeHyung KooIl-Kyu Choi
Advisor
구재형
Co-Advisor(s)
Il-Kyu Choi
Issued Date
2024
Awarded Date
2024-08-01
Citation
Jae Won Hwang. (2024). Extra-nasal odorant receptors regulate the progression of glioblastoma. doi: 10.22677/THESIS.200000806490
Type
Thesis
Description
Glioblastoma, Tumor-associated microglia and macrophages, Odorant receptors, Ligand
Table Of Contents
Ⅰ. INTRODUCTION 1
ⅠⅠ. MATERIALS AND METHODS 7
IⅠⅠ. RESULTS
3.1 The pathophysiological role of OR5V1 in GBM 12
3.1.1 To establish GL261-luc syngeneic mouse model 12
3.1.2 To demonstrate the function of OR5V1 in GBM 14
3.1.3 To investigate the function of microglial-specific OR5V1 in GBM 16
3.1.4 To determine the anti-tumor effect of OR5V1’s agonist in GBM 20
3.2 The pathophysiological role of OR51E2 in GBM 25
3.2.1 To demonstrate the function of OR51E2 in GBM 25
ⅠV. DISCUSSION 29
V. REFERENCES 36
URI
http://hdl.handle.net/20.500.11750/57607
http://dgist.dcollection.net/common/orgView/200000806490
DOI
10.22677/THESIS.200000806490
Degree
Master
Department
Department of New Biology
Publisher
DGIST
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