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Screening and functional characterization of extra-nasal odorant receptor antagonists
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Title
Screening and functional characterization of extra-nasal odorant receptor antagonists
Alternative Title
비강 외 후각수용체의 길항제 선별 및 그 기능 규명
DGIST Authors
JunHee KimJaeHyung KooKyungmoo Yea
Advisor
구재형
Co-Advisor(s)
Kyungmoo Yea
Issued Date
2024
Awarded Date
2024-08-01
Citation
JunHee Kim. (2024). Screening and functional characterization of extra-nasal odorant receptor antagonists. doi: 10.22677/THESIS.200000805501
Type
Thesis
Description
Odorant receptor, antagonists, screening
Table Of Contents
List of Contents

Abstract i
List of contents ii


Ⅰ. Introduction 1
ⅠI. MATERIALS AND METHOD 4
IIⅠ. RESULTS
3.1 Establishment of a Stable Cell Line Expressing OR5V1 9
3.2 Primary Screening for OR5V1 Antagonists 11
3.3 Secondary Screening for OR5V1 Antagonists 16
3.4 Antagonists Inhibit OR5V1 Function in Primary Cells 19
3.5 Effects of Antagonists on Different Types of Agonists in OR5V1. 22
3.6 Agonist Identification from Secondary screening 25
ⅠV. DISCUSSION 28
V REFERENCES 30
URI
http://hdl.handle.net/20.500.11750/57610
http://dgist.dcollection.net/common/orgView/200000805501
DOI
10.22677/THESIS.200000805501
Degree
Master
Department
Department of New Biology
Publisher
DGIST
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