The Giese reaction of alkyl bromides using amine carboxyboranes

Abstract

Amine carboxyborane enabled efficient halogen atom transfer (XAT) with 1 degrees, 2 degrees, and 3 degrees alkyl bromides, resulting in Giese addition products with various electron-deficient double bonds. Moreover, direct addition of several boryl radicals was also possible using several ligated carboxyboranes.