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| DC Field | Value | Language |
|---|---|---|
| dc.contributor.author | 노수정 | - |
| dc.contributor.author | 백문창 | - |
| dc.contributor.author | 류수연 | - |
| dc.contributor.author | 예경무 | - |
| dc.contributor.author | 정도경 | - |
| dc.date.accessioned | 2025-07-24T19:10:17Z | - |
| dc.date.available | 2025-07-24T19:10:17Z | - |
| dc.identifier.uri | https://scholar.dgist.ac.kr/handle/20.500.11750/58715 | - |
| dc.description.abstract | The present invention relates to a composition for preventing or treating cancer diseases, comprising IL-2 or an expression promoter or activator thereof as an active ingredient. In the present invention, it has been found that when IL-2 is applied to cancer cells, IL-2 inhibits secretion of exosomes derived from cancer cells and inhibits expression of PD-L1 that induces immune escape of T cells, thereby enhancing an anticancer effect. In contrast to conventional techniques that exhibit immune anti-cancer effects by activating cytotoxic T cells, IL-2 has also been found to have an anti-cancer effect directly on cancer cells. Therefore, IL-2 or an expression promoter or activator thereof can be advantageously used in a composition for preventing or treating cancer diseases. | - |
| dc.title | Composition for enhancing anti-cancer effect comprising exosome PD-L1 expression inhibitor as active ingredient | - |
| dc.title.alternative | COMPOSITION COMPRISING INHIBITOR AGAINST EXPRESSION OF EXOSOMAL PD-L1 AS ACTIVE INGREDIENT FOR ENHANCING ANTICANCER EFFECT | - |
| dc.type | Patent | - |
| dc.identifier.bibliographicCitation | 노수정. Composition for enhancing anti-cancer effect comprising exosome PD-L1 expression inhibitor as active ingredient. | - |
| dc.publisher.country | CC | - |
| dc.identifier.patentApplicationNumber | 202080070149.0 | - |
| dc.date.application | 2020-09-18 | - |
| dc.identifier.patentRegistrationNumber | 114599396 | - |
| dc.date.registration | 2022-06-07 | - |
| dc.contributor.assignee | ESSENTIAL-SCHOOL COOPERATION GROUP IN NORTH UNIVERSITY,QINGBEI SCIENCE AND TECHNOLOGY YARD OF QINGBEI | - |
| dc.type.iprs | 특허 | - |