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Novel anti-c-MPL antibodies and uses thereof
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dc.contributor.author 예경무 -
dc.contributor.author 신지원 -
dc.contributor.author 박세광 -
dc.contributor.author 정지영 -
dc.contributor.author 김민정 -
dc.date.accessioned 2025-07-28T18:10:11Z -
dc.date.available 2025-07-28T18:10:11Z -
dc.identifier.uri https://scholar.dgist.ac.kr/handle/20.500.11750/58764 -
dc.description.abstract The present invention relates to a novel anti-c-MPL antibody and a use thereof, and more particularly, to an anti-c-MPL antibody having an effect of increasing platelet production and the number thereof by maturation of megakaryocytes in bone marrow, and a use thereof. The novel anti-c-MPL antibody (2R13) of the present invention has a longer half-life period than conventional therapeutic agents as a polymer material, and has the advantages of low autoantibody production and low immunogenicity as an antibody reagent. In addition, the present invention increases the platelet count in a patient suffering from immune thrombocytopenia that induces a chronic disease or complication, and thus can be used as a therapeutic agent for thrombocytopenia. -
dc.title Novel anti-c-MPL antibodies and uses thereof -
dc.title.alternative NOVEL ANTI-C-MPL ANTIBODY AND USE THEREOF -
dc.type Patent -
dc.publisher.country CC -
dc.identifier.patentApplicationNumber 202180089138.1 -
dc.date.application 2021-11-09 -
dc.identifier.patentRegistrationNumber 116745321 -
dc.date.registration 2023-09-12 -
dc.contributor.assignee DAEGU GYEONGBUK INSTITUTE OF SCIENCE AND TECHNOLOGY,INDUSTRY-ACADEMIC COOPERATION FOUNDATION, KOSHIN UNIVERSITY,INJE UNIVERSITY INDUSTRY-ACADEMIC COOPERATION FOUNDATION -
dc.type.iprs 특허 -
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예경무
Yea, Kyungmoo예경무

Department of New Biology

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