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| DC Field | Value | Language |
|---|---|---|
| dc.contributor.author | 정종원 | - |
| dc.contributor.author | 이범용 | - |
| dc.contributor.author | 예경무 | - |
| dc.date.accessioned | 2025-07-30T09:40:11Z | - |
| dc.date.available | 2025-07-30T09:40:11Z | - |
| dc.identifier.uri | https://scholar.dgist.ac.kr/handle/20.500.11750/58803 | - |
| dc.description.abstract | The present invention relates to GFRAL antagonistic antibodies having improved affinity and uses thereof, and more specifically, the present invention relates to anti-GFRAL antibodies having improved affinity or antigen-binding fragments thereof, comprising a heavy chain CDR and a light chain CDR of specific sequences. The anti-GFRAL antibody having improved affinity exhibits a higher binding capacity to GFRAL protein than a conventional anti-GFRAL antibody, and thus is expected to be effectively used for improving or treating cancer-related anorexia or cachexia syndrome and side effects of chemotherapy anti-cancer drugs. | - |
| dc.title | GFRAL antagonistic antibodies with improved affinity and uses thereof | - |
| dc.title.alternative | GFRAL-ANTAGONISTIC ANTIBODY HAVING IMPROVED AFFINITY, AND USE THEREOF | - |
| dc.type | Patent | - |
| dc.publisher.country | CC | - |
| dc.identifier.patentApplicationNumber | 202280064331.4 | - |
| dc.date.application | 2022-09-05 | - |
| dc.identifier.patentRegistrationNumber | 118043355 | - |
| dc.date.registration | 2024-05-14 | - |
| dc.contributor.assignee | DAEGU GYEONGBUK INSTITUTE OF SCIENCE AND TECHNOLOGY | - |
| dc.type.iprs | 특허 | - |
