Title

Development and Functional Analysis of USP14-Targeting Chimeric Compounds

Alternative Title

USP14 표적 키메라 화합물의 개발 및 기능 분석

DGIST Authors

Gyosun Lee ; Byung-Hoon Lee ; Younghoon Kee

Advisor

이병훈

Co-Advisor(s)

Younghoon Kee

Issued Date

2025

Awarded Date

2025-08-01

Type

Thesis

Description

Targeted Protein Degradation (TPD), PROTAC, Proteasome-Proximity Induced Degrader (PPID), USP14, CRBN, BRD4, proteasome, NRF1

Table Of Contents

List of Contents

Abstract i
List of contents ii
List of figures iii

Ⅰ. Introduction 1
II. Materials and Methods 6
III. Results 10
IV. Discussion 21

References 26
Korean Summary 29

URI

https://scholar.dgist.ac.kr/handle/20.500.11750/59819
http://dgist.dcollection.net/common/orgView/200000890192

DOI

10.22677/THESIS.200000890192

Degree

Master

Department

Department of New Biology

Publisher

DGIST

Show Full Item Record