Cited 42 time in webofscience Cited 38 time in scopus

Compliance with Saliva Collection Protocol in Healthy Volunteers: Strategies for Managing Risk and Errors

Title
Compliance with Saliva Collection Protocol in Healthy Volunteers: Strategies for Managing Risk and Errors
Authors
Bhattarai, Kashi RajKim, Hyung-RyongChae, Han-Jung
DGIST Authors
Bhattarai, Kashi Raj; Kim, Hyung-Ryong; Chae, Han-Jung
Issue Date
2018-05
Citation
International Journal of Medical Sciences, 15(8), 823-831
Type
Article
Article Type
Review
Author Keywords
Saliva collectionhealthy volunteerssalivary proteomicspsychological stresssampling errorsrisk management
Keywords
SQUAMOUS-CELL CARCINOMAAGE-RELATED-CHANGESFLOW-RATEALPHA-AMYLASEWHOLE-SALIVAYOUNG-ADULTSPSYCHOSOCIAL STRESSSAMPLE COLLECTIONXEROSTOMIABIOMARKERS
ISSN
1449-1907
Abstract
Salivary bioscience technologies such as electrophoresis are widely applied for diagnosing systemic health status. Diagnosis using a saliva sample has emerged as a preferred technique since the sample is easy to collect and the method is inexpensive and non-invasive. Salivary diagnostics have even been identified as potential substitutes for serum protein biomarkers. However, the optimal protocol for collecting saliva has not yet been established. In many scientific settings, such as randomized controlled trials, sampling and statistical errors often occur when handling samples from healthy volunteers. These errors can be due to the psychological behavior of the volunteers, subject nonadherence, questionnaire characteristics, collection methods, and/or sample processing. The purpose of the review presented here is to outline the strategies for managing the risk factors and to minimize the sampling errors during saliva collection in healthy volunteers. © Ivyspring International Publisher.
URI
http://hdl.handle.net/20.500.11750/6671
DOI
10.7150/ijms.25146
Publisher
Ivyspring International Publisher
Files:
Collection:
ETC1. Journal Articles


qrcode mendeley

Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.

BROWSE