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A highly sensitive and selective biosensor based on nitrogen-doped graphene for non-enzymatic detection of uric acid and dopamine at biological pH value
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dc.contributor.author Foroughi, Faranak ko
dc.contributor.author Rahsepar, Mansour ko
dc.contributor.author Kim, Hasuck ko
dc.date.accessioned 2018-10-11T02:02:46Z -
dc.date.available 2018-10-11T02:02:46Z -
dc.date.created 2018-10-04 -
dc.date.issued 2018-10 -
dc.identifier.citation Journal of Electroanalytical Chemistry, v.827, pp.34 - 41 -
dc.identifier.issn 1572-6657 -
dc.identifier.uri http://hdl.handle.net/20.500.11750/9334 -
dc.description.abstract Few layered graphene nanosheets were successfully doped with nitrogen through microwave irradiation and thoroughly characterized by using electron microscopy, Raman spectroscopy and X-ray photoelectron spectroscopy. The electrochemical efficiency of N-doped graphene toward enzyme-free detection of uric acid (UA) and dopamine (DA) at neutral pH (7.4) was studied by chronoamperometry and cyclic voltammetry measurements. At working potential of +0.3 V (vs. Ag/AgCl), N-doped graphene electrode revealed ultra-high sensitivity of 2.06 mA mM−1 cm−2 and low limit of detection (LOD) of 0.13 μM within a concentration range of 0 to 0.6 mM for UA detection. Also, at very higher potential of +1.8 V (vs. Ag/AgCl), N-doped graphene sensor exhibited a highly selective response toward DA with very low LOD of 4.5 nM and high sensitivity of 7.63 mA mM−1 cm−2 in a broad linear concentration range from 0.1 to 100 μM. Furthermore, the performance of UA and DA sensors in the real blood sample was satisfactory. © 2018 -
dc.language English -
dc.publisher Elsevier B.V. -
dc.subject Graphene -
dc.subject N-doping -
dc.subject Cyclic voltammetry -
dc.subject Dopamine biosensor -
dc.subject Uric acid biosensor -
dc.subject Microwave synthesis -
dc.subject Cyclic voltammetry -
dc.subject Dopamine biosensor -
dc.subject Graphene -
dc.subject Microwave synthesis -
dc.subject N-doping -
dc.subject Uric acid biosensor -
dc.subject Amines -
dc.subject Biosensors -
dc.subject Chronoamperometry -
dc.subject Cyclic voltammetry -
dc.subject Doping (additives) -
dc.subject Graphite electrodes -
dc.subject Microwave irradiation -
dc.subject Neurophysiology -
dc.subject Nitrogen -
dc.subject Organic acids -
dc.subject X ray photoelectron spectroscopy -
dc.subject Linear concentration -
dc.subject Microwave synthesis -
dc.subject N-Doping -
dc.subject Nitrogen doped graphene -
dc.subject Non-enzymatic detection -
dc.subject Ultra-high-sensitivity -
dc.subject Uric acid biosensors -
dc.subject Voltammetry measurements -
dc.subject Graphene -
dc.title A highly sensitive and selective biosensor based on nitrogen-doped graphene for non-enzymatic detection of uric acid and dopamine at biological pH value -
dc.type Article -
dc.identifier.doi 10.1016/j.jelechem.2018.09.008 -
dc.identifier.wosid 000447479500005 -
dc.identifier.scopusid 2-s2.0-85052912930 -
dc.type.local Article(Overseas) -
dc.type.rims ART -
dc.identifier.bibliographicCitation Foroughi, Faranak. (2018-10). A highly sensitive and selective biosensor based on nitrogen-doped graphene for non-enzymatic detection of uric acid and dopamine at biological pH value. doi: 10.1016/j.jelechem.2018.09.008 -
dc.description.journalClass 1 -
dc.contributor.nonIdAuthor Foroughi, Faranak -
dc.contributor.nonIdAuthor Rahsepar, Mansour -
dc.identifier.citationVolume 827 -
dc.identifier.citationStartPage 34 -
dc.identifier.citationEndPage 41 -
dc.identifier.citationTitle Journal of Electroanalytical Chemistry -
dc.type.journalArticle Article -
dc.description.isOpenAccess N -
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