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The Potential Roles of Extracellular Vesicles in Cigarette Smoke-Associated Diseases

Title
The Potential Roles of Extracellular Vesicles in Cigarette Smoke-Associated Diseases
Authors
Ryu, A-ReumKim, Do HyunKim, EunjooLee, Mi Young
DGIST Authors
Kim, Eunjoo
Issue Date
2018-11
Citation
Oxidative Medicine and Cellular Longevity
Type
Article
Article Type
Review
Keywords
OBSTRUCTIVE PULMONARY-DISEASESQUAMOUS-CELL CARCINOMAORAL-CANCER DETECTIONLUNG-CANCERTOBACCO-SMOKESTEM-CELLSENDOTHELIAL MICROPARTICLESMEMBRANE MICROVESICLESEPITHELIAL-CELLSEXOSOMES
ISSN
1942-0900
Abstract
Cigarette smoke contains more than 4,500 chemicals; most of which are highly reactive free radicals, which induce proinflammatory and carcinogenic reactions. Numerous efforts have focused extensively on the role of cigarette smoking as a cause of many diseases. Extracellular vesicles and exosomes have recently received increasing interest for their diagnostic and therapeutic roles in many diseases. However, research done on the role of extracellular vesicles and exosomes on cigarette smoke-induced chronic disease is still in its infancy. In this review, we summarize the recently addressed roles of extracellular vesicles and exosomes in the pathogenesis of cigarette smoke-related diseases, such as chronic obstructive pulmonary disease, cardiovascular disease, lung cancer, and oral cancer. Moreover, their potential utilization and future prospects as diagnostic biomarkers for cigarette smoke-related diseases are described. © 2018 A-Reum Ryu et al.
URI
http://hdl.handle.net/20.500.11750/9487
DOI
10.1155/2018/4692081
Publisher
Hindawi Limited
Related Researcher
  • Author Kim, Eunjoo  
  • Research Interests Biomarker, liquid biopsy, molecular diagnosis, nanobiosensor, drug delivery, exosome
Files:
There are no files associated with this item.
Collection:
Companion Diagnostics and Medical Technology Research Group1. Journal Articles


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