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The Potential Roles of Extracellular Vesicles in Cigarette Smoke-Associated Diseases
- The Potential Roles of Extracellular Vesicles in Cigarette Smoke-Associated Diseases
- Ryu, A-Reum; Kim, Do Hyun; Kim, Eunjoo; Lee, Mi Young
- DGIST Authors
- Kim, Eunjoo
- Issue Date
- Oxidative Medicine and Cellular Longevity
- Article Type
- OBSTRUCTIVE PULMONARY-DISEASE; SQUAMOUS-CELL CARCINOMA; ORAL-CANCER DETECTION; LUNG-CANCER; TOBACCO-SMOKE; STEM-CELLS; ENDOTHELIAL MICROPARTICLES; MEMBRANE MICROVESICLES; EPITHELIAL-CELLS; EXOSOMES
- Cigarette smoke contains more than 4,500 chemicals; most of which are highly reactive free radicals, which induce proinflammatory and carcinogenic reactions. Numerous efforts have focused extensively on the role of cigarette smoking as a cause of many diseases. Extracellular vesicles and exosomes have recently received increasing interest for their diagnostic and therapeutic roles in many diseases. However, research done on the role of extracellular vesicles and exosomes on cigarette smoke-induced chronic disease is still in its infancy. In this review, we summarize the recently addressed roles of extracellular vesicles and exosomes in the pathogenesis of cigarette smoke-related diseases, such as chronic obstructive pulmonary disease, cardiovascular disease, lung cancer, and oral cancer. Moreover, their potential utilization and future prospects as diagnostic biomarkers for cigarette smoke-related diseases are described. © 2018 A-Reum Ryu et al.
- Hindawi Limited
- Related Researcher
Biomarker, liquid biopsy, molecular diagnosis, nanobiosensor, drug delivery, exosome
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- Companion Diagnostics and Medical Technology Research Group1. Journal Articles
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