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Showing results 1 to 27 of 27

Article
Activation Dynamics of the Neurotensin G Protein-Coupled Receptor 1
  • Cong, Xiaojing ; 
  • Golebiowski, Jerome ; 
  • Fiorucci, Sebastien
  • 2018-08
  • Cong, Xiaojing. (2018-08). Activation Dynamics of the Neurotensin G Protein-Coupled Receptor 1. doi: 10.1021/acs.jctc.8b00216
  • American Chemical Society
  • View : 654
  • Download : 0
Article
Agonists of G-Protein-Coupled Odorant Receptors Are Predicted from Chemical Features
  • Bushdid, C. ; 
  • De March, C.A. ; 
  • Fiorucci, S. ; 
  • Matsunami, H. ; 
  • Golebiowski, Jerome
  • 2018-05
  • Bushdid, C. (2018-05). Agonists of G-Protein-Coupled Odorant Receptors Are Predicted from Chemical Features. doi: 10.1021/acs.jpclett.8b00633
  • American Chemical Society
  • View : 522
  • Download : 0
Article
Allosteric Modulation Mechanism of the mGIuR(5) Transmembrane Domain
  • Cong, Xiaojing ; 
  • Cheron, Jean-Baptiste ; 
  • Golebiowski, Jerome ; 
  • Antonczak, Serge ; 
  • Fiorucci, Sebastien
  • 2019-06
  • Cong, Xiaojing. (2019-06). Allosteric Modulation Mechanism of the mGIuR(5) Transmembrane Domain. doi: 10.1021/acs.jcim.9b00045
  • American Chemical Society
  • View : 648
  • Download : 0
Article
Allosteric Na+-binding site modulates CXCR4 activation
  • Cong, Xiaojing ; 
  • Golebiowski, Jerome
  • 2018-10
  • Cong, Xiaojing. (2018-10). Allosteric Na+-binding site modulates CXCR4 activation. Physical Chemistry Chemical Physics, 20(38), 24915–24920. doi: 10.1039/c8cp04134b
  • Royal Society of Chemistry
  • View : 551
  • Download : 0

Chemical features mining provides new descriptive structure-odor relationships

Article
Chemical features mining provides new descriptive structure-odor relationships
  • Licon, Carmen C. ; 
  • Bosc, Guillaume ; 
  • Sabri, Mohammed ; 
  • Mantel, Marylou ; 
  • Fournel, Arnaud ; 
  • Bushdid, Caroline ; 
  • Golebiowski, Jerome ; 
  • Robardet, Celine ; 
  • Plantevit, Marc ; 
  • Kaytoue, Mehdi ; 
    • et al
  • 2019-04
  • Licon, Carmen C. (2019-04). Chemical features mining provides new descriptive structure-odor relationships. doi: 10.1371/journal.pcbi.1006945
  • Public Library of Science
  • View : 438
  • Download : 160
Article
Conserved Residues Control the T1R3-Specific Allosteric Signaling Pathway of the Mammalian Sweet-Taste Receptor
  • Cheron, Jean-Baptiste ; 
  • Soohoo, Amanda ; 
  • Wang, Yi ; 
  • Golebiowski, Jerome ; 
  • Antonczak, Serge ; 
  • Jiang, Peihua ; 
  • Fiorucci, Sebastien
  • 2019-06
  • Cheron, Jean-Baptiste. (2019-06). Conserved Residues Control the T1R3-Specific Allosteric Signaling Pathway of the Mammalian Sweet-Taste Receptor. doi: 10.1093/chemse/bjz015
  • Oxford University Press
  • View : 448
  • Download : 0
Article
Discovery and Mechanism of Action of Small Molecule Inhibitors of Ceramidases**
  • Healey, Robert D. ; 
  • Saied, Essa M. ; 
  • Cong, Xiaojing ; 
  • Karsai, Gergely ; 
  • Gabellier, Ludovic ; 
  • Saint-Paul, Julie ; 
  • Del Nero, Elise ; 
  • Jeannot, Sylvain ; 
  • Drapeau, Marion ; 
  • Fontanel, Simon ; 
    • et al
  • 2022-01
  • Healey, Robert D. (2022-01). Discovery and Mechanism of Action of Small Molecule Inhibitors of Ceramidases**. Angewandte Chemie - International Edition, 61(2). doi: 10.1002/anie.202109967
  • John Wiley & Sons Ltd.
  • View : 372
  • Download : 0

Elucidation of the structural basis for ligand binding and translocation in conserved insect odorant receptor co-receptors

Article
Elucidation of the structural basis for ligand binding and translocation in conserved insect odorant receptor co-receptors
  • Pacalon, Jody ; 
  • Audic, Guillaume ; 
  • Magnat, Justine ; 
  • Philip, Manon ; 
  • Golebiowski, Jerome ; 
  • Moreau, Christophe J. ; 
  • Topin, Jérémie
  • 2023-12
  • Pacalon, Jody. (2023-12). Elucidation of the structural basis for ligand binding and translocation in conserved insect odorant receptor co-receptors. Nature Communications, 14(1). doi: 10.1038/s41467-023-44058-5
  • Springer Nature
  • View : 250
  • Download : 4
Article
Extracellular loop 2 of G protein–coupled olfactory receptors is critical for odorant recognition
  • Yu, Yiqun ; 
  • Ma, Zhenjie ; 
  • Pacalon, Jody ; 
  • Xu, Lun ; 
  • Li, Weihao ; 
  • Belloir, Christine ; 
  • Topin, Jeremie ; 
  • Briand, Loic ; 
  • Golebiowski, Jerome ; 
  • Cong, Xiaojing
  • 2022-09
  • Yu, Yiqun. (2022-09). Extracellular loop 2 of G protein–coupled olfactory receptors is critical for odorant recognition. Journal of Biological Chemistry, 298(9). doi: 10.1016/j.jbc.2022.102331
  • American Society for Biochemistry and Molecular Biology Inc.
  • View : 333
  • Download : 0
Article
Functional molecular switches of mammalian G protein-coupled bitter-taste receptors
  • Topin, Jérémie ; 
  • Bouysset, Cédric ; 
  • Pacalon, Jody ; 
  • Kim, Yiseul ; 
  • Rhyu, Mee-Ra ; 
  • Fiorucci, Sébastien ; 
  • Golebiowski, Jerome
  • 2021-12
  • Topin, Jérémie. (2021-12). Functional molecular switches of mammalian G protein-coupled bitter-taste receptors. Cellular and Molecular Life Sciences, 78(23), 7605–7615. doi: 10.1007/s00018-021-03968-7
  • Springer Science and Business Media Deutschland GmbH
  • View : 384
  • Download : 0
Conference
Identification Of Entry Pathway And Binding Site Of Insect Odorant Co-Receptor
  • Topin, Jeremie ; 
  • Pacalon, Jody ; 
  • Audic, Guillaume ; 
  • Golebiowski, Jerome ; 
  • Moreau, Christophe
  • 2022-04-22
  • Topin, Jeremie. (2022-04-22). Identification Of Entry Pathway And Binding Site Of Insect Odorant Co-Receptor. Annual Meeting of the Association for Chemoreception Sciences, AChemS XLIV, 80–80. doi: 10.1093/chemse/bjac031
  • Association for Chemoreception Sciences(AChemS)
  • View : 91
  • Download : 0
Conference
Integrative structural modeling reveals functional molecular switches of human G protein-coupled bittertaste receptors
  • Fiorucci, Sebastien ; 
  • Bouysset, Cedric ; 
  • Kim, Ysul ; 
  • Pacalon, Jody ; 
  • Rhyu, Meera ; 
  • Golebiowski, Jerome ; 
  • Topin, Jeremie
  • 2022-04-21
  • Fiorucci, Sebastien. (2022-04-21). Integrative structural modeling reveals functional molecular switches of human G protein-coupled bittertaste receptors. Annual Meeting of the Association for Chemoreception Sciences, AChemS XLIV, 15–16. doi: 10.1093/chemse/bjac031
  • Association for chemoreception Sciences(AChemS)
  • View : 55
  • Download : 0
Article
Interactions among key residues regulate mammalian odorant receptor trafficking
  • Xu, Rui ; 
  • Cong, Xiaojing ; 
  • Zheng, Qian ; 
  • Xu, Lun ; 
  • Ni, Mengjue J. ; 
  • March, Claire A. ; 
  • Matsunami, Hiroaki ; 
  • Golebiowski, Jerome ; 
  • Ma, Minghong ; 
  • Yu, Yiqun
  • 2022-07
  • Xu, Rui. (2022-07). Interactions among key residues regulate mammalian odorant receptor trafficking. FASEB Journal, 36(7). doi: 10.1096/fj.202200116RR
  • Federation of American Societies for Experimental Biology
  • View : 189
  • Download : 0
Article
Large-Scale G Protein-Coupled Olfactory Receptor-Ligand Pairing
  • Cong, Xiaojing ; 
  • Ren, Wenwen ; 
  • Pacalon, Jody ; 
  • Xu, Rui ; 
  • Xu, Lun ; 
  • Li, Xuewen ; 
  • de March, Claire A. ; 
  • Matsunami, Hiroaki ; 
  • Yu, Hongmeng ; 
  • Yu, Yiqun ; 
    • et al
  • 2022-03
  • Cong, Xiaojing. (2022-03). Large-Scale G Protein-Coupled Olfactory Receptor-Ligand Pairing. ACS Central Science, 8(3), 379–387. doi: 10.1021/acscentsci.1c01495
  • American Chemical Society
  • View : 299
  • Download : 0

Machine learning decodes chemical features to identify novel agonists of a moth odorant receptor

Article
Machine learning decodes chemical features to identify novel agonists of a moth odorant receptor
  • Caballero-Vidal, Gabriela ; 
  • Bouysset, Cédric ; 
  • Grunig, Hubert ; 
  • Fiorucci, Sébastien ; 
  • Montagné, Nicolas ; 
  • Golebiowski, Jerome ; 
  • Jacquin-Joly, Emmanuelle
  • 2020-02
  • Caballero-Vidal, Gabriela. (2020-02). Machine learning decodes chemical features to identify novel agonists of a moth odorant receptor. doi: 10.1038/s41598-020-58564-9
  • Nature Publishing Group
  • View : 523
  • Download : 172
Article
Mammalian class I odorant receptors exhibit a conserved vestibular-binding pocket
  • Bushdid, Caroline ; 
  • de March, Claire A. ; 
  • Topin, Jeremie ; 
  • Do, Matthew ; 
  • Matsunami, Hiroaki ; 
  • Golebiowski, Jerome
  • 2019-03
  • Bushdid, Caroline. (2019-03). Mammalian class I odorant receptors exhibit a conserved vestibular-binding pocket. doi: 10.1007/s00018-018-2996-4
  • Birkhauser Verlag AG
  • View : 758
  • Download : 0
Article
Metal Ions Activate the Human Taste Receptor TAS2R7
  • Wang, Yi ; 
  • Zajac, Amanda L. ; 
  • Lei, Weiwei ; 
  • Christensen, Carol M. ; 
  • Margolskee, Robert F. ; 
  • Bouysset, Cedric ; 
  • Golebiowski, Jerome ; 
  • Zhao, Huabin ; 
  • Fiorucci, Sebastien ; 
  • Jiang, Peihua
  • 2019-06
  • Wang, Yi. (2019-06). Metal Ions Activate the Human Taste Receptor TAS2R7. Chemical Senses, 44(5), 339–347. doi: 10.1093/chemse/bjz024
  • Oxford University Press
  • View : 772
  • Download : 0
Article
Molecular insights into the biased signaling mechanism of the mu-opioid receptor
  • Cong, Xiaojing ; 
  • Maurel, Damien ; 
  • Demene, Helene ; 
  • Vasiliauskaite-Brooks, Ieva ; 
  • Hagelberger, Joanna ; 
  • Peysson, Fanny ; 
  • Saint-Paul, Julie ; 
  • Golebiowski, Jerome ; 
  • Granier, Sebastien ; 
  • Sounier, Remy
  • 2021-10
  • Cong, Xiaojing. (2021-10). Molecular insights into the biased signaling mechanism of the mu-opioid receptor. Molecular Cell, 81(20), 4165–4175. doi: 10.1016/j.molcel.2021.07.033
  • Cell Press
  • View : 388
  • Download : 0
Article
Odorant Receptor 7D4 Activation Dynamics
  • deMarch, C.A. ; 
  • Topin, J. ; 
  • Bruguera, E. ; 
  • Novikov, G. ; 
  • Ikegami, K. ; 
  • Matsunami, H. ; 
  • Golebiowski, Jerome
  • 2018-04
  • deMarch, C.A. (2018-04). Odorant Receptor 7D4 Activation Dynamics. doi: 10.1002/anie.201713065
  • John Wiley & Sons Ltd.
  • View : 845
  • Download : 0

Olfactory receptor 10J5 responding to Alpha-cedrene regulates hepatic steatosis via the cAMP-PKA pathway

Article
Olfactory receptor 10J5 responding to Alpha-cedrene regulates hepatic steatosis via the cAMP-PKA pathway
  • Tong, Tao ; 
  • Ryu, Sang Eun ; 
  • Min, Yeojin ; 
  • De March, Claire A. ; 
  • Bushdid, Caroline ; 
  • Golebiowski, Jerome ; 
  • Moon, Cheil ; 
  • Park, Taesun
  • 2017-08
  • Tong, Tao. (2017-08). Olfactory receptor 10J5 responding to Alpha-cedrene regulates hepatic steatosis via the cAMP-PKA pathway. Scientific Reports, 7(1). doi: 10.1038/s41598-017-10379-x
  • Nature Publishing Group
  • View : 885
  • Download : 308
Article
Reverse chemical ecology in a moth: machine learning on odorant receptors identifies new behaviorally active agonists
  • Caballero-Vidal, Gabriela ; 
  • Bouysset, Cedric ; 
  • Gevar, Jeremy ; 
  • Mbouzid, Hayat ; 
  • Nara, Celine ; 
  • Delaroche, Julie ; 
  • Golebiowski, Jerome ; 
  • Montagne, Nicolas ; 
  • Fiorucci, Sebastien ; 
  • Jacquin-Joly, Emmanuelle
  • 2021-10
  • Caballero-Vidal, Gabriela. (2021-10). Reverse chemical ecology in a moth: machine learning on odorant receptors identifies new behaviorally active agonists. Cellular and Molecular Life Sciences, 78(19–20), 6593–6603. doi: 10.1007/s00018-021-03919-2
  • Springer Science and Business Media Deutschland GmbH
  • View : 379
  • Download : 0

Smell and taste changes are early indicators of the COVID-19 pandemic and political decision effectiveness

Article
Smell and taste changes are early indicators of the COVID-19 pandemic and political decision effectiveness
  • Pierron, Denis ; 
  • Pereda-Loth, Veronica ; 
  • Mantel, Marylou ; 
  • Moranges, Maelle ; 
  • Bignon, Emmanuelle ; 
  • Alva, Omar ; 
  • Kabous, Julie ; 
  • Heiske, Margit ; 
  • Pacalon, Jody ; 
  • David, Renaud ; 
    • et al
  • 2020-10
  • Pierron, Denis. (2020-10). Smell and taste changes are early indicators of the COVID-19 pandemic and political decision effectiveness. Nature Communications, 11(1), 5152. doi: 10.1038/s41467-020-18963-y
  • Nature Research
  • View : 397
  • Download : 66
Article
Structure-odour relationships reviewed in the postgenomic era
  • de March, Claire A. ; 
  • Ryu, SangEun ; 
  • Sicard, Gilles ; 
  • Moon, Cheil ; 
  • Golebiowski, Jerome
  • 2015-09
  • de March, Claire A. (2015-09). Structure-odour relationships reviewed in the postgenomic era. Flavour and Fragrance Journal, 30(5), 342–361. doi: 10.1002/ffj.3249
  • Wiley Blackwell
  • View : 997
  • Download : 0
Conference
The Functional Role of the Third Extracellular Loop of Mammalian Odorant Receptors in Ligand Binding
  • Shim, Tammy ; 
  • Pacalon, Jody ; 
  • WonCheol, Kim ; 
  • Cong, Xiaojing ; 
  • Topin, Jeremie ; 
  • Golebiowski, Jerome ; 
  • Moon, Cheil
  • 2023-04-22
  • Shim, Tammy. (2023-04-22). The Functional Role of the Third Extracellular Loop of Mammalian Odorant Receptors in Ligand Binding. Annual Meeting of the Association for Chemoreception Sciences, AChemS XLV, 121–121. doi: 10.1093/chemse/bjad029
  • Association for Chemoreception Sciences
  • View : 163
  • Download : 0
Article
The Third Extracellular Loop of Mammalian Odorant Receptors Is Involved in Ligand Binding
  • Shim, Tammy ; 
  • Pacalon, Jody ; 
  • Kim, Won-Cheol ; 
  • Cong, Xiaojing ; 
  • Topin, Jeremie ; 
  • Golebiowski, Jerome ; 
  • Moon, Cheil
  • 2022-10
  • Shim, Tammy. (2022-10). The Third Extracellular Loop of Mammalian Odorant Receptors Is Involved in Ligand Binding. International Journal of Molecular Sciences, 23(20). doi: 10.3390/ijms232012501
  • MDPI
  • View : 466
  • Download : 0
Article
Those molecules that awaken our taste buds; [Ces molécules qui éveillent nos papilles]
  • Chéron, Jean Baptiste ; 
  • Golebiowski, Jerome ; 
  • Antonczak, Serge ; 
  • Briand, Loïc ; 
  • Fiorucci, Sébastien
  • 2017-03
  • Chéron, Jean Baptiste. (2017-03). Those molecules that awaken our taste buds; [Ces molécules qui éveillent nos papilles]. Actualite Chimique, (416), 11–18.
  • Societe Francaise de Chimie
  • View : 99
  • Download : 0

Zebrafish olfactory receptors ORAs differentially detect bile acids and bile salts

Article
Zebrafish olfactory receptors ORAs differentially detect bile acids and bile salts
  • Cong, Xiaojing ; 
  • Zheng, Qian ; 
  • Ren, Wenwen ; 
  • Cheron, Jean-Baptiste ; 
  • Fiorucci, Sebastien ; 
  • Wen, Tieqiao ; 
  • Zhang, Chunbo ; 
  • Yu, Hongmeng ; 
  • Golebiowski, Jerome ; 
  • Yu, Yiqun
  • 2019-04
  • Cong, Xiaojing. (2019-04). Zebrafish olfactory receptors ORAs differentially detect bile acids and bile salts. doi: 10.1074/jbc.RA118.006483
  • American Society for Biochemistry and Molecular Biology Inc.
  • View : 608
  • Download : 116
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