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HEXA-018, a Novel Inducer of Autophagy, Rescues TDP-43 Toxicity in Neuronal Cells

Article
HEXA-018, a Novel Inducer of Autophagy, Rescues TDP-43 Toxicity in Neuronal Cells
  • Lee, Shinrye ; 
  • Jo, Myungjin ; 
  • Lee, Hye Eun ; 
  • Jeon, Yu-Mi ; 
  • Kim, Seyeon ; 
  • Kwon, Younghwi ; 
  • Woo, Junghwa ; 
  • Han, Shin ; 
  • Mun, Ji Young ; 
  • Kim, Hyung-Jun
  • 2021-12
  • Lee, Shinrye. (2021-12). HEXA-018, a Novel Inducer of Autophagy, Rescues TDP-43 Toxicity in Neuronal Cells. doi: 10.3389/fphar.2021.747975
  • Frontiers Media S.A.
  • View : 483
  • Download : 178
Article
Neuroprotective Effects of Protein Tyrosine Phosphatase 1B Inhibition against ER Stress-Induced Toxicity
  • Jeon, Yu-Mi ; 
  • Lee, Shinrye ; 
  • Kim, Seyeon ; 
  • Kwon, Younghwi ; 
  • Kim, Kiyoung ; 
  • Chung, Chang Geon ; 
  • Lee, Seongsoo ; 
  • Lee, Sung Bae ; 
  • Kim, Hyung-Jun
  • 2017-04
  • Jeon, Yu-Mi. (2017-04). Neuroprotective Effects of Protein Tyrosine Phosphatase 1B Inhibition against ER Stress-Induced Toxicity. doi: 10.14348/molcells.2017.2320
  • 한국분자세포생물학회
  • View : 751
  • Download : 0
Thesis
Protective Effects of PTP1B Inhibition on Astrocytic TDP-43-induced Inflammation and Neurotoxicity
  • Kim, Seyeon
  • 2018
  • Kim, Seyeon. (2018). Protective Effects of PTP1B Inhibition on Astrocytic TDP-43-induced Inflammation and Neurotoxicity. doi: 10.22677/thesis.200000006985
  • DGIST
  • View : 638
  • Download : 0
Article
PTK2 regulates tau-induced neurotoxicity via phosphorylation of p62 at Ser403
  • Lee, Shinrye ; 
  • Jo, Myungjin ; 
  • Kwon, Younghwi ; 
  • Jeon, Yu-Mi ; 
  • Kim, Seyeon ; 
  • Lee, Kea Joo ; 
  • Kim, Hyung-Jun
  • 2023-04
  • Lee, Shinrye. (2023-04). PTK2 regulates tau-induced neurotoxicity via phosphorylation of p62 at Ser403. Journal of Neurogenetics, 37(1–2), 10–19. doi: 10.1080/01677063.2022.2114471
  • Taylor & Francis
  • View : 372
  • Download : 0
Article
PTK2/FAK regulates UPS impairment via SQSTM1/p62 phosphorylation in TARDBP/TDP-43 proteinopathies
  • Lee, Shinrye ; 
  • Jeon, Yu-Mi ; 
  • Cha, Sun Joo ; 
  • Kim, Seyeon ; 
  • Kwon, Younghwi ; 
  • Jo, Myungjin ; 
  • Jang, You-Na ; 
  • Lee, Seongsoo ; 
  • Kim, Jaekwang ; 
  • Kim, Sang Ryong ; 
    • et al
  • 2020-08
  • Lee, Shinrye. (2020-08). PTK2/FAK regulates UPS impairment via SQSTM1/p62 phosphorylation in TARDBP/TDP-43 proteinopathies. Autophagy, 16(8), 1396–1412. doi: 10.1080/15548627.2019.1686729
  • Taylor and Francis
  • View : 722
  • Download : 0

The overexpression of TDP-43 in astrocytes causes neurodegeneration via a PTP1B-mediated inflammatory response

Article
The overexpression of TDP-43 in astrocytes causes neurodegeneration via a PTP1B-mediated inflammatory response
  • Lee, Shinrye ; 
  • Kim, Seyeon ; 
  • Kang, Ha-Young ; 
  • Lim, Hye Ryeong ; 
  • Baik, Seungyeob ; 
  • Jo, Myungjin ; 
  • Jeon, Yu-Mi ; 
  • Kim, Sang Ryong ; 
  • Kim, Kiyoung ; 
  • Ha, Chang Man ; 
    • et al
  • 2020-10
  • Lee, Shinrye. (2020-10). The overexpression of TDP-43 in astrocytes causes neurodegeneration via a PTP1B-mediated inflammatory response. doi: 10.1186/s12974-020-01963-6
  • BioMed Central Ltd
  • View : 533
  • Download : 85

The Role of Glial Mitochondria in α-Synuclein Toxicity

Article
The Role of Glial Mitochondria in α-Synuclein Toxicity
  • Jeon, Yu-Mi ; 
  • Kwon, Younghwi ; 
  • Jo, Myungjin ; 
  • Lee, Shinrye ; 
  • Kim, Seyeon ; 
  • Kim, Hyung-Jun
  • 2020-11
  • Jeon, Yu-Mi. (2020-11). The Role of Glial Mitochondria in α-Synuclein Toxicity. doi: 10.3389/fcell.2020.548283
  • Frontiers Media S.A.
  • View : 523
  • Download : 73

The Role of HDAC6 in TDP-43-Induced Neurotoxicity and UPS Impairment

Article
The Role of HDAC6 in TDP-43-Induced Neurotoxicity and UPS Impairment
  • Lee, Shinrye ; 
  • Kwon, Younghwi ; 
  • Kim, Seyeon ; 
  • Jo, Myungjin ; 
  • Jeon, Yu-Mi ; 
  • Cheon, Mookyung ; 
  • Lee, Seongsoo ; 
  • Kim, Sang Ryong ; 
  • Kim, Kiyoung ; 
  • Kim, Hyung-Jun
  • 2020-11
  • Lee, Shinrye. (2020-11). The Role of HDAC6 in TDP-43-Induced Neurotoxicity and UPS Impairment. doi: 10.3389/fcell.2020.581942
  • Frontiers Media S.A.
  • View : 607
  • Download : 155

The role of TDP-43 propagation in neurodegenerative diseases: integrating insights from clinical and experimental studies

Article
The role of TDP-43 propagation in neurodegenerative diseases: integrating insights from clinical and experimental studies
  • Jo, Myungjin ; 
  • Lee, Shinrye ; 
  • Jeon, Yu-Mi ; 
  • Kim, Seyeon ; 
  • Kwon, Younghwi ; 
  • Kim, Hyung-Jun
  • 2020-10
  • Experimental & Molecular Medicine, v.52, no.10, pp.1652 - 1662
  • Springer Nature
  • View : 529
  • Download : 40

Vitamin B12 Reduces TDP-43 Toxicity by Alleviating Oxidative Stress and Mitochondrial Dysfunction

Article
Vitamin B12 Reduces TDP-43 Toxicity by Alleviating Oxidative Stress and Mitochondrial Dysfunction
  • Jeon, Yu.-Mi. ; 
  • Kwon, Younghwi ; 
  • Lee, Shinrye. ; 
  • Kim, Seyeon ; 
  • Jo, Myungjin. ; 
  • Lee, Seongsoo. ; 
  • Kim, Sang Ryong. ; 
  • Kim, Kiyoung. ; 
  • Kim, Hyung Jun
  • 2022-01
  • Jeon, Yu.-Mi. (2022-01). Vitamin B12 Reduces TDP-43 Toxicity by Alleviating Oxidative Stress and Mitochondrial Dysfunction. doi: 10.3390/antiox11010082
  • MDPI AG
  • View : 527
  • Download : 164
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