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Clinical Efficacy of ONC201 in H3K27M-Mutant Diffuse Midline Gliomas Is Driven by Disruption of Integrated Metabolic and Epigenetic Pathways

Article
Clinical Efficacy of ONC201 in H3K27M-Mutant Diffuse Midline Gliomas Is Driven by Disruption of Integrated Metabolic and Epigenetic Pathways
  • Venneti, Sriram ; 
  • Kawakibi, Abed Rahman ; 
  • Ji, Sunjong ; 
  • Waszak, Sebastian M. ; 
  • Sweha, Stefan R. ; 
  • Mota, Mateus ; 
  • Pun, Matthew ; 
  • Deogharkar, Akash ; 
  • Chung, Chan ; 
  • Tarapore, Rohinton S. ; 
    • et al
  • 2023-11
  • Venneti, Sriram. (2023-11). Clinical Efficacy of ONC201 in H3K27M-Mutant Diffuse Midline Gliomas Is Driven by Disruption of Integrated Metabolic and Epigenetic Pathways. Cancer Discovery, 13(11), 2370–2393. doi: 10.1158/2159-8290.cd-23-0131
  • American Association for Cancer Research
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  • Download : 234
Conference
Lactate metabolism in H3K27M mutant diffuse midline gliomas
  • Lum, Joanna ; 
  • Deogharkar, Akash ; 
  • Chung, Chan ; 
  • Sajjakulnukit, Peter ; 
  • Lyssiotis, Costas ; 
  • Venneti, Sriram
  • 2025-11-19
  • 30th Annual Meeting of the Society for Neuro-Oncology and 7th Quadrennial Meeting of WFNOS, pp.v432 - v433
  • Society for Neuro-Oncology, World Federation of Neuro-Oncology Societies
  • View : 171
  • Download : 0

Therapeutic targeting of differentiation-state dependent metabolic vulnerabilities in diffuse midline glioma

Article
Therapeutic targeting of differentiation-state dependent metabolic vulnerabilities in diffuse midline glioma
  • Mbah, Nneka E. ; 
  • Myers, Amy L. ; 
  • Sajjakulnukit, Peter ; 
  • Chung, Chan ; 
  • Thompson, Joyce K. ; 
  • Hong, Hanna S. ; 
  • Giza, Heather ; 
  • Dang, Derek ; 
  • Nwosu, Zeribe C. ; 
  • Shan, Mengrou ; 
    • et al
  • 2024-10
  • Mbah, Nneka E. (2024-10). Therapeutic targeting of differentiation-state dependent metabolic vulnerabilities in diffuse midline glioma. Nature Communications, 15(1). doi: 10.1038/s41467-024-52973-4
  • Nature Publishing Group
  • View : 382
  • Download : 102
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