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Clinical Efficacy of ONC201 in H3K27M-Mutant Diffuse Midline Gliomas Is Driven by Disruption of Integrated Metabolic and Epigenetic Pathways

  • Venneti, Sriram
  • Kawakibi, Abed Rahman
  • Ji, Sunjong
  • Waszak, Sebastian M.
  • Sweha, Stefan R.
  • Mota, Mateus
  • Pun, Matthew
  • Deogharkar, Akash
  • Chung, Chan
  • Tarapore, Rohinton S.
  • et al
  • 2023-11
  • Venneti, Sriram. (2023-11). Clinical Efficacy of ONC201 in H3K27M-Mutant Diffuse Midline Gliomas Is Driven by Disruption of Integrated Metabolic and Epigenetic Pathways. Cancer Discovery, 13(11), 2370–2393. doi: 10.1158/2159-8290.cd-23-0131
  • American Association for Cancer Research
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  • Download : 104
  • Sweha, Stefan R.
  • Chung, Chan
  • Natarajan, Siva Kumar
  • Panwalkar, Pooja
  • Pun, Matthew
  • Ghali, Amer
  • Bayliss, Jill
  • Pratt, Drew
  • Shankar, Anand
  • Ravikumar, Visweswaran
  • et al
  • 2021-10
  • Sweha, Stefan R. (2021-10). Epigenetically defined therapeutic targeting in H3.3G34R/V high-grade gliomas. Science Translational Medicine, 13(615). doi: 10.1126/scitranslmed.abf7860
  • American Association for the Advancement of Science
  • View : 456
  • Download : 0
  • Mota, Mateus
  • Sweha, Stefan R.
  • Pun, Matt
  • Natarajan, Siva Kumar
  • Ding, Yujie
  • Chung, Chan
  • Hawes, Debra
  • Yang, Fusheng
  • Judkins, Alexander R.
  • Samajdar, Susanta
  • et al
  • 2023-04
  • Mota, Mateus. (2023-04). Targeting SWI/SNF ATPases in H3.3K27M diffuse intrinsic pontine gliomas. Proceedings of the National Academy of Sciences of the United States of America, 120(18). doi: 10.1073/pnas.2221175120
  • National Academy of Sciences
  • View : 315
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Therapeutic targeting of differentiation-state dependent metabolic vulnerabilities in diffuse midline glioma

  • Mbah, Nneka E.
  • Myers, Amy L.
  • Sajjakulnukit, Peter
  • Chung, Chan
  • Thompson, Joyce K.
  • Hong, Hanna S.
  • Giza, Heather
  • Dang, Derek
  • Nwosu, Zeribe C.
  • Shan, Mengrou
  • et al
  • 2024-10
  • Mbah, Nneka E. (2024-10). Therapeutic targeting of differentiation-state dependent metabolic vulnerabilities in diffuse midline glioma. Nature Communications, 15(1). doi: 10.1038/s41467-024-52973-4
  • Nature Publishing Group
  • View : 204
  • Download : 45
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