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Showing results 1 to 9 of 9

Article
Chronic oral administration of ibrutinib prevents long-term memory deficits and reduces AD pathology and neuroinflammatory responses in a mouse model of AD
  • Lee, Hyun-ju ; 
  • Kang, Sora ; 
  • Jeong, Yoo Joo ; 
  • Park, Jin-Hee ; 
  • Hwang, Jeong-Woo ; 
  • Gu, Chan-Hu ; 
  • Jung, Tae-Mi ; 
  • Oh, Seokjun ; 
  • Jang, Ji-Yeong ; 
  • Hoe, Hyang-Sook
  • 2025-07
  • Molecular Brain, v.18, no.1
  • BioMed Central
  • View : 996
  • Download : 0
Article
Donepezil ameliorates Aβ pathology but not tau pathology in 5xFAD mice
  • Choi, H.-J. ; 
  • Park, J.-H. ; 
  • Jeong, Y.J. ; 
  • Hwang, J.-W. ; 
  • Lee, S. ; 
  • Lee, H. ; 
  • Seol, E. ; 
  • Kim, I.-W. ; 
  • Cha, B.-Y. ; 
  • Seo, J. ; 
    • et al
  • 2022-07
  • Choi, H.-J. (2022-07). Donepezil ameliorates Aβ pathology but not tau pathology in 5xFAD mice. Molecular Brain, 15(1). doi: 10.1186/s13041-022-00948-1
  • BioMed Central
  • View : 266
  • Download : 0

Felodipine attenuates neuroinflammatory responses and tau hyperphosphorylation through JNK/P38 signaling in tau-overexpressing AD mice

Article
Felodipine attenuates neuroinflammatory responses and tau hyperphosphorylation through JNK/P38 signaling in tau-overexpressing AD mice
  • Hwang, Jeong-Woo ; 
  • Kim, Jeongha ; 
  • Park, Jin-Hee ; 
  • Nam, Jinhan ; 
  • Jang, Ji-Yeong ; 
  • Jo, Aran ; 
  • Lee, Hyun-Ju ; 
  • Hoe, Hyang-Sook
  • 2024-09
  • Hwang, Jeong-Woo. (2024-09). Felodipine attenuates neuroinflammatory responses and tau hyperphosphorylation through JNK/P38 signaling in tau-overexpressing AD mice. Molecular Brain, 17(1). doi: 10.1186/s13041-024-01137-y
  • BioMed Central
  • View : 290
  • Download : 35
Article
Gait Ignition Failure in JNPL3 Human Tau-mutant Mice
  • Jang, HoChung ; 
  • Ryu, Jung Hwa ; 
  • Shin, Kyung Min ; 
  • Seo, Na-young ; 
  • Kim, Gyu Hyun ; 
  • Huh, Yang Hoon ; 
  • Pae, Ae Nim ; 
  • Lee, Kye Joo
  • 2019-06
  • Jang, HoChung. (2019-06). Gait Ignition Failure in JNPL3 Human Tau-mutant Mice. doi: 10.5607/en.2019.28.3.404
  • Korean Society for Neurodegenerative Disease
  • View : 678
  • Download : 0

Inhibition of CDK4/6 regulates AD pathology, neuroinflammation and cognitive function through DYRK1A/STAT3 signaling

Article
Inhibition of CDK4/6 regulates AD pathology, neuroinflammation and cognitive function through DYRK1A/STAT3 signaling
  • Lee, Hyun-ju ; 
  • Hoe, Hyang-Sook
  • 2023-04
  • Lee, Hyun-ju. (2023-04). Inhibition of CDK4/6 regulates AD pathology, neuroinflammation and cognitive function through DYRK1A/STAT3 signaling. Pharmacological Research, 190. doi: 10.1016/j.phrs.2023.106725
  • Academic Press
  • View : 191
  • Download : 88

L-DOPA regulates neuroinflammation and Aβ pathology through NEP and ADAM17 in a mouse model of AD

Article
L-DOPA regulates neuroinflammation and Aβ pathology through NEP and ADAM17 in a mouse model of AD
  • Lee, Hyun-ju ; 
  • Nam, Jinhan ; 
  • Hwang, Jeong-Woo ; 
  • Park, Jin-Hee ; 
  • Jeong, Yoo Joo ; 
  • Jang, Ji-Yeong ; 
  • Kim, Su-Jeong ; 
  • Jo, A-Ran ; 
  • Hoe, Hyang-Sook
  • 2024-04
  • Lee, Hyun-ju. (2024-04). L-DOPA regulates neuroinflammation and Aβ pathology through NEP and ADAM17 in a mouse model of AD. Molecular Brain, 17(1). doi: 10.1186/s13041-024-01092-8
  • BioMed Central
  • View : 106
  • Download : 35
Article
Profiling tyrosine kinase inhibitors as AD therapeutics in a mouse model of AD
  • Lee, Hyun-ju ; 
  • Hwang, Jeong-Woo ; 
  • Park, Jin-Hee ; 
  • Jeong, Yoo Joo ; 
  • Jang, Ji-Yeong ; 
  • Hoe, Hyang-Sook
  • 2023-08
  • Lee, Hyun-ju. (2023-08). Profiling tyrosine kinase inhibitors as AD therapeutics in a mouse model of AD. Molecular Brain, 16(1). doi: 10.1186/s13041-023-01051-9
  • BioMed Central
  • View : 131
  • Download : 0
Article
PTK2 regulates tau-induced neurotoxicity via phosphorylation of p62 at Ser403
  • Lee, Shinrye ; 
  • Jo, Myungjin ; 
  • Kwon, Younghwi ; 
  • Jeon, Yu-Mi ; 
  • Kim, Seyeon ; 
  • Lee, Kea Joo ; 
  • Kim, Hyung-Jun
  • 2023-04
  • Lee, Shinrye. (2023-04). PTK2 regulates tau-induced neurotoxicity via phosphorylation of p62 at Ser403. Journal of Neurogenetics, 37(1–2), 10–19. doi: 10.1080/01677063.2022.2114471
  • Taylor & Francis
  • View : 409
  • Download : 0

The dopamine analogue CA140 alleviates AD pathology, neuroinflammation, and rescues synaptic/cognitive functions by modulating DRD1 signaling or directly binding to Abeta

Article
The dopamine analogue CA140 alleviates AD pathology, neuroinflammation, and rescues synaptic/cognitive functions by modulating DRD1 signaling or directly binding to Abeta
  • Chae, Sehyun ; 
  • Lee, Hyun-ju ; 
  • Lee, Ha-Eun ; 
  • Kim, Jieun ; 
  • Jeong, Yoo Joo ; 
  • Lin, Yuxi ; 
  • Kim, Hye Yun ; 
  • Leriche, Geoffray ; 
  • Ehrlich, Rachel S. ; 
  • Lingl, Sascha Castro ; 
    • et al
  • 2024-08
  • Chae, Sehyun. (2024-08). The dopamine analogue CA140 alleviates AD pathology, neuroinflammation, and rescues synaptic/cognitive functions by modulating DRD1 signaling or directly binding to Abeta. Journal of Neuroinflammation, 21(1). doi: 10.1186/s12974-024-03180-x
  • BioMed Central
  • View : 255
  • Download : 43
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