Full metadata record
| DC Field | Value | Language |
|---|---|---|
| dc.contributor.advisor | 이성배 | - |
| dc.contributor.author | Sung Soon Park | - |
| dc.date.accessioned | 2019-08-22T16:00:13Z | - |
| dc.date.available | 2019-08-22T16:00:13Z | - |
| dc.date.issued | 2019 | - |
| dc.identifier.uri | http://dgist.dcollection.net/common/orgView/200000219092 | en_US |
| dc.identifier.uri | http://hdl.handle.net/20.500.11750/10450 | - |
| dc.description | TDP-43, Golgi outposts, Splicing, Rab GTPases, endo-lysosomal pathway | - |
| dc.description.statementofresponsibility | prohibition | - |
| dc.description.tableofcontents | Abstract ····················································································i List of contents ········································································ii List of tables ··········································································iii List of figures ·········································································iv I. Introduction········································································1 II. Materials and Methods ·························································3 III. Results···········································································10 3.1 dTDP-43 overexpression increases the number of Golgi outposts ······················10 3.2 Nuclear dTDP-43 regulates the number of dendritic GOPs through pre-mRNA splicing function ················································································28 3.3 Increased level of Rab GTPase effectors by dTDP-43 overexpression contributes to GOP synthesis ···············································································43 3.4 dTDP-43-induced GOPs regulate membrane trafficking to late endo-lysosomes and plasma membrane in dendrites···························································58 IV. Discussion·······································································66 V. References ·······································································72 VI. Summary in Korean··························································76 |
- |
| dc.format.extent | 87 | - |
| dc.language | eng | - |
| dc.publisher | DGIST | - |
| dc.source | /home/dspace/dspace53/upload/200000219092.pdf | - |
| dc.title | TDP-43 regulates local membrane trafficking through Golgi outposts in Drosophila neurons | - |
| dc.type | Thesis | - |
| dc.identifier.doi | 10.22677/thesis.200000219092 | - |
| dc.description.degree | Master | - |
| dc.contributor.department | Department of Brain and Cognitive Sciences | - |
| dc.contributor.coadvisor | Ho Min Kim | - |
| dc.date.awarded | 2019-08 | - |
| dc.publisher.location | Daegu | - |
| dc.description.database | dCollection | - |
| dc.citation | XT.BM 박54 201908 | - |
| dc.date.accepted | 2019-07-01 | - |
| dc.contributor.alternativeDepartment | 뇌인지과학전공 | - |
| dc.embargo.liftdate | 2020-09-01 | - |
| dc.contributor.affiliatedAuthor | Lee, Sung Bae | - |
| dc.contributor.affiliatedAuthor | Park, Sung Soon | - |
| dc.contributor.affiliatedAuthor | Kim, Ho Min | - |
| dc.contributor.alternativeName | 박성순 | - |
| dc.contributor.alternativeName | Sung Bae Lee | - |
| dc.contributor.alternativeName | 김호민 | - |
- Files in This Item:
-
There are no files associated with this item.
- Appears in Collections:
- Department of Brain Sciences Theses Master
Items in Repository are protected by copyright, with all rights reserved, unless otherwise indicated.