Cited 5 time in webofscience Cited 4 time in scopus

Magnetically Actuated SiCN-Based Ceramic Microrobot for Guided Cell Delivery

Title
Magnetically Actuated SiCN-Based Ceramic Microrobot for Guided Cell Delivery
Authors
Gyak, Ki-WonJeon, S.Ha, LauraKim, Sang WonKim, Jin-YoungLee, K.-S.Choi, H.Kim, Dong-Pyo
DGIST Authors
Kim, Jin-YoungChoi, H.
Issue Date
2019-11
Citation
Advanced Healthcare Materials, 8(21)
Type
Article
Article Type
Article
Author Keywords
biocompatible materialscell deliveryceramic microrobotsmagnetic nanoparticlessilicon carbonitride
Keywords
FABRICATION
ISSN
2192-2640
Abstract
A silicon carbonitride (SICN) ceramic microrobot, biocompatible and magnetically activable, is developed for the delivery of viable cells to defective tissue by sequential steps of microstructuring, magnetization, and cell loading. The ceramic carrier of porous cylindrical framework is fabricated by 3D laser lithography using a photocurable preceramic polymer, chemically modified polyvinylsilazane, and subsequent pyrolysis at 600 °C under an inert atmosphere. Magnetic nanoparticles (MNP) are integrated into the surface-modified ceramic carrier by thiol-ene click reaction. Finally, the microrobot is loaded with fibroblast cells, which can be guided by a rotating external magnetic field. The proposed ceramic microrobot is mechanically durable, adequately controllable with external magnetic field, and quite compatible with mammalian cells. © 2019 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim
URI
http://hdl.handle.net/20.500.11750/10918
DOI
10.1002/adhm.201900739
Publisher
Wiley-VCH Verlag
Related Researcher
  • Author Choi, Hongsoo Bio-Micro Robotics Lab
  • Research Interests Micro/Nano robot; Neural prostheses; MEMS; BMI; MEMS/NEMS; BioMEMS; MEMS 초음파 트랜스듀스; 인공와우
Files:
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Collection:
Department of Robotics EngineeringBio-Micro Robotics Lab1. Journal Articles


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