The role of the posterior parietal cortex in visually-evoked defensive response
- Title
- The role of the posterior parietal cortex in visually-evoked defensive response
- Author(s)
- Hak Yeong Kim
- DGIST Authors
- Lee, Hyosang ; Kim, Hak Yeong ; Koo, Ja Wook
- Advisor
- 이효상
- Co-Advisor(s)
- Ja Wook Koo
- Issued Date
- 2020
- Awarded Date
- 2020-02
- Type
- Thesis
- Description
- Posterior parietal cortex, Zona incerta, Defense, Innate fear, Cognitive function
- Table Of Contents
-
I. INTRODUCTION 1
1.1 Defensive behavior 1
1.2 Looming disc stimuli 2
1.3 Posterior parietal cortex 3
II. MATERIALS AND METHODS 6
III. RESULTS 11
3.1. Validate the effectiveness of the looming disk paradigm 11
3.2. PPC ablation mice showed differences in pattern maintenance and adaptation compared to control mice 18
3.3. Chemogenetic inactivation of PPC changes the visually-evoked defensive response, similar to the Casp3-mediated ablation 22
3.4. Chemogenetic activation of PPC changes the visually-evoked defensive response 23
3.5. Behavioral characterization of mice after activation/inactivation of PPC by CNO administration 29
3.6. The monitoring of PPC upstream and downstream region using tracing experiments 31
3.7 Functional identification of ZI role in controlling visual-threat defense behavior by PPC 33
IV. DISCUSSION 40
V. REFERENCES 44
VI. SUMMARY (국문요약) 46
- URI
-
http://dgist.dcollection.net/common/orgView/200000286223
http://hdl.handle.net/20.500.11750/11914
- Degree
- Master
- Department
- Brain and Cognitive Sciences
- Publisher
- DGIST
- Related Researcher
-
-
Lee, Hyosang
- Research Interests Neuronal circuit mechanisms underlying emotional behaviors; 정서적 행동을 매개하는 신경회로 연구
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- Files in This Item:
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- Appears in Collections:
- Department of Brain Sciences Theses Master
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