Lee, Sunju. (2020). Studies on Critical Roles of cIAP1 in the Olfactory System. doi: 10.22677/Theses.200000282063
Type
Thesis
Description
cIAP1 (cellular inhibitor of apoptosis 1), the olfactory system, homeostasis, terminal differentiation, cell death
Table Of Contents
CHAPTER 1. INTRODUCTION 1 1.1 cIAP1 1 1.1.1 IAPs (inhibitor of apoptosis proteins) 1 1.1.1.1 Structure of IAP family 1.1.1.2 Roles of IAP family 1.1.2 cIAP1 3 1.1.2.1 Functions of cIAP1 1.1.2.2 cIAP1, cIAP2 and XIAP 1.2 The olfactory system 5 1.2.1 The anatomy of the olfactory system 5 1.2.1.1 Olfactory epithelium 1.2.1.2 Olfactory bulb 1.2.2 Regeneration of the olfactory system 7 1.3 Purpose of the project 8 CHAPTER 2. MATERIALS AND METHODS 9 CHAPTER 3. RESULTS 12 3.1 cIAP1 KO mice 12 3.2 Protein activation 12 3.2.1 cell-death related proteins 3.3 Morphological observation 14 3.3.1 Cell death in the OE 3.3.2 Synaptic connection in the OB 3.4 Behavioral observation 20 CHAPTER 4. DISCUSSION 21 CHAPTER 5. FURTHER STUDIES 25 REFERENCES 26 ABSTRACT IN KOREAN 33
