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Recent progress on peripheral neural interface technology towards bioelectronic medicine

Title
Recent progress on peripheral neural interface technology towards bioelectronic medicine
Authors
Cho, Young JunPark, JaeuLee, ChengkuoLee, Sanghoon
DGIST Authors
Cho, Young Jun; Park, Jaeu; Lee, Chengkuo; Lee, Sanghoon
Issue Date
2020-11
Citation
Bioelectronic Medicine, 6(23), 1-10
Type
Article
Article Type
Review
Author Keywords
Ultrasound stimulationMagnetic stimulationBioelectronic medicinePeripheral nerve interfaceWireless neural interfaceEnergy harvesters
ISSN
2332-8886
Abstract
Modulation of the peripheral nervous system (PNS) has a great potential for therapeutic intervention as well as restore bodily functions. Recent interest has focused on autonomic nerves, as they regulate extensive functions implicated in organ physiology, chronic disease state and appear tractable to targeted modulation of discrete nerve units. Therapeutic interventions based on specific bioelectronic neuromodulation depend on reliable neural interface to stimulate and record autonomic nerves. Furthermore, the function of stimulation and recording requires energy which should be delivered to the interface. Due to the physiological and anatomical challenges of autonomic nerves, various forms of this active neural interface need to be developed to achieve next generation of neural interface for bioelectronic medicine. In this article, we present an overview of the state-of-the-art for peripheral neural interface technology in relation to autonomic nerves. Also, we reveal the current status of wireless neural interface for peripheral nerve applications. Recent studies of a novel concept of self-sustainable neural interface without battery and electronic components are presented. Finally, the recent results of non-invasive stimulation such as ultrasound and magnetic stimulation are covered and the perspective of the future research direction is provided.
URI
http://hdl.handle.net/20.500.11750/12644
DOI
10.1186/s42234-020-00059-z
Publisher
BMC
Related Researcher
  • Author Lee, SangHoon Neuro-Interfaced Robotics Lab
  • Research Interests Neural interface; Neuroprosthetics; Bioelectronics; Robotics
Files:
Collection:
Department of Robotics EngineeringNeuro-Interfaced Robotics Lab1. Journal Articles


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