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dc.contributor.author Jang, Jung-Hee -
dc.contributor.author Park, Sangsoo -
dc.contributor.author An, Jinung -
dc.contributor.author Choi, Jong-duk -
dc.contributor.author Seol, In Chan -
dc.contributor.author Park, Gunhyuk -
dc.contributor.author Lee, Seung Hyun -
dc.contributor.author Moon, Young -
dc.contributor.author Kang, Weechang -
dc.contributor.author Jung, Eun-Sun -
dc.contributor.author Cha, Ji-yun -
dc.contributor.author Kim, Chan-young -
dc.contributor.author Kim, Siyeon -
dc.contributor.author Jung, In Chul -
dc.contributor.author Yoo, Horyong -
dc.date.accessioned 2021-01-22T07:20:54Z -
dc.date.available 2021-01-22T07:20:54Z -
dc.date.created 2020-11-26 -
dc.date.issued 2020-12 -
dc.identifier.citation Neurorehabilitation and Neural Repair, v.34, no.12, pp.1111 - 1123 -
dc.identifier.issn 1545-9683 -
dc.identifier.uri http://hdl.handle.net/20.500.11750/12736 -
dc.description.abstract Background: Parkinson’s disease (PD) leads to impaired mobility and limited independence. Objective: We investigated the effects of acupuncture on gait disturbance and analyzed hemodynamic changes caused by acupuncture in the cerebral cortex of patients with PD. Methods: Participants (n = 26) with gait disturbance due to PD were randomly assigned to the intervention (acupuncture twice a week for 4 weeks + conventional therapy) or control (conventional therapy) groups. We analyzed gait parameters using the GAITRite system and hemodynamic responses in the cerebral cortices using functional near-infrared spectroscopy, Unified Parkinson’s Disease Rating Scale (UPDRS) scores, neurotransmitter levels, as well as the immediate effects of acupuncture in patients with PD. Results: The participants tended to walk with hypometric gait (high cadence, short steps) overground. After acupuncture treatment, those in the intervention group showed a significant reduction in cadence and the UPDRS scores involving “walking and balance” compared with those in the control group (P =.004 and P =.020, respectively); the stride, swing, and single support times were significantly increased (P =.006, P =.001, and P =.001, respectively). Oxyhemoglobin levels in the intervention group while walking on a treadmill were significantly increased in the prefrontal and supplementary motor areas. The oxyhemoglobin levels in the prefrontal cortex and swing time revealed significant positive correlations. Conclusions: Our findings indicated that acupuncture tended to improve hypometric gait and rearranged activation of the cerebral cortex. Thus, acupuncture may be a useful complementary treatment for gait disturbance, including hypometric gait, in patients with PD. Trial Registration Number. Clinical Research Information Service (KCT0002603), https://cris.nih.go.kr/cris/index.jsp © The Author(s) 2020. -
dc.language English -
dc.publisher Sage Science Press -
dc.title Gait Disturbance Improvement and Cerebral Cortex Rearrangement by Acupuncture in Parkinson’s Disease: A Pilot Assessor-Blinded, Randomized, Controlled, Parallel-Group Trial -
dc.type Article -
dc.identifier.doi 10.1177/1545968320969942 -
dc.identifier.wosid 000594704700005 -
dc.identifier.scopusid 2-s2.0-85096174264 -
dc.contributor.localid 080021 -
dc.type.local Article(Overseas) -
dc.type.rims ART -
dc.description.journalClass 1 -
dc.citation.publicationname Neurorehabilitation and Neural Repair -
dc.contributor.nonIdAuthor Jang, Jung-Hee -
dc.contributor.nonIdAuthor Park, Sangsoo -
dc.contributor.nonIdAuthor Choi, Jong-duk -
dc.contributor.nonIdAuthor Seol, In Chan -
dc.contributor.nonIdAuthor Park, Gunhyuk -
dc.contributor.nonIdAuthor Lee, Seung Hyun -
dc.contributor.nonIdAuthor Moon, Young -
dc.contributor.nonIdAuthor Kang, Weechang -
dc.contributor.nonIdAuthor Jung, Eun-Sun -
dc.contributor.nonIdAuthor Cha, Ji-yun -
dc.contributor.nonIdAuthor Kim, Chan-young -
dc.contributor.nonIdAuthor Kim, Siyeon -
dc.contributor.nonIdAuthor Jung, In Chul -
dc.contributor.nonIdAuthor Yoo, Horyong -
dc.identifier.citationVolume 34 -
dc.identifier.citationNumber 12 -
dc.identifier.citationStartPage 1111 -
dc.identifier.citationEndPage 1123 -
dc.identifier.citationTitle Neurorehabilitation and Neural Repair -
dc.type.journalArticle Article -
dc.description.isOpenAccess N -
dc.subject.keywordAuthor Parkinson’s disease -
dc.subject.keywordAuthor gait -
dc.subject.keywordAuthor acupuncture -
dc.subject.keywordAuthor near infrared spectroscopy -
dc.contributor.affiliatedAuthor Jang, Jung-Hee -
dc.contributor.affiliatedAuthor Park, Sangsoo -
dc.contributor.affiliatedAuthor An, Jinung -
dc.contributor.affiliatedAuthor Choi, Jong-duk -
dc.contributor.affiliatedAuthor Seol, In Chan -
dc.contributor.affiliatedAuthor Park, Gunhyuk -
dc.contributor.affiliatedAuthor Lee, Seung Hyun -
dc.contributor.affiliatedAuthor Moon, Young -
dc.contributor.affiliatedAuthor Kang, Weechang -
dc.contributor.affiliatedAuthor Jung, Eun-Sun -
dc.contributor.affiliatedAuthor Cha, Ji-yun -
dc.contributor.affiliatedAuthor Kim, Chan-young -
dc.contributor.affiliatedAuthor Kim, Siyeon -
dc.contributor.affiliatedAuthor Jung, In Chul -
dc.contributor.affiliatedAuthor Yoo, Horyong -
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Division of Intelligent Robotics Brain Robot Augmented InteractioN(BRAIN) Laboratory 1. Journal Articles

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