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Long-term characterization of neural electrodes based on parylene-caulked polydimethylsiloxane substrate
- Long-term characterization of neural electrodes based on parylene-caulked polydimethylsiloxane substrate
- Jeong, Jinmo; Chou, Namsun; Kim, Sohee
- DGIST Authors
- Kim, Sohee
- Issue Date
- Biomedical Microdevices, 18(3), 1-9
- Article Type
- Biomedical Applications; Convergence of Numerical Methods; Electrical Stability; Electro-Chemical Electrodes; Electro-Chemical Impedance Spectroscopy (EIS); Electrochemical Impedance Spectroscopy (EIS); Electrodes; Implantable Electrodes; Mechanical Properties; Medical Applications; Microchannels; Neural Electrode; Parylene; Parylene-Caulked PDMS (PC-PDMS); Parylenes; Phosphate-Buffered Saline Solutions; Polydimethylsiloxane (PDMS); Silicones; Stability; Stretchability; Surface Electrode; Tensile Testing; Water Absorption
- This study investigates the mechanical and long-term electrical properties of parylene-caulked polydimethylsiloxane (PDMS) as a substrate for implantable electrodes. The parylene-caulked PDMS is a structure where particles of parylene fill the porous surface of PDMS. This material is expected to have low water absorption and desirable mechanical properties such as flexibility and elasticity that are beneficial in many biomedical applications. To evaluate the mechanical property and electrical stability of parylene-caulked PDMS for potential in-vivo uses, tensile tests were conducted firstly, which results showed that the mechanical strength of parylene-caulked PDMS was comparable to that of native PDMS. Next, surface electrodes based on parylene-caulked PDMS were fabricated and their impedance was measured in phosphate-buffered saline (PBS) solution at 36.5 °C over seven months. The electrodes based on parylene-caulked PDMS exhibited the improved stability in impedance over time than native PDMS. Thus, with improved electrical stability in wet environment and preserved mechanical properties of PDMS, the electrodes based on parylene-caulked PDMS are expected to be suitable for long-term in-vivo applications. © 2016, Springer Science+Business Media New York.
- Related Researcher
Neural Interfaces & MicroSystems Lab
Neural interface; Brain interface; Bio MEMS; Soft MEMS; Stretchable electronics; Zebrafish electrophysiology
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- Department of Robotics EngineeringNeural Interfaces & MicroSystems Lab1. Journal Articles
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