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Protocol for quantitative assessment of social cooperation in mice

Title
Protocol for quantitative assessment of social cooperation in mice
Authors
Shin, JungsuKo, Jaewon
DGIST Authors
Shin, Jungsu; Ko, Jaewon
Issue Date
2021-03
Citation
STAR Protocols, 2(1), 100305
Type
Article
Author Keywords
Model organismsNeuroscience
ISSN
2666-1667
Abstract
Social cooperation in rodents was recently validated in rats, and we recently successfully applied a modified automated analysis to mice. Here, we describe a detailed procedure for using this paradigm in mice that relies on reward-based mutual communication that is automatically detected by a software algorithm embedded in the custom-made equipment. We also describe exemplary results of analyses in mice as a guide to broader neuroscience research applications employing transgenic knockout mice modeling neuropsychiatric disorders and mice of various ages. For complete details on the use and execution of this protocol, please refer to Han et al. (2020). © 2021 The Author(s)
URI
http://hdl.handle.net/20.500.11750/13823
DOI
10.1016/j.xpro.2021.100305
Publisher
Cell Press
Related Researcher
  • Author Ko, Jaewon Laboratory of Synapse Formation and Function
  • Research Interests Synapse Formation and Function; Neural Circuits; 뇌질환; animal model
Files:
Collection:
Department of Brain SciencesLaboratory of Synapse Formation and Function1. Journal Articles


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