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Combined Analysis of the Time-Resolved Transcriptome and Proteome of Plant Pathogen Xanthomonas oryzae pv. oryzae

Title
Combined Analysis of the Time-Resolved Transcriptome and Proteome of Plant Pathogen Xanthomonas oryzae pv. oryzae
Authors
Kim, SeunghwanJang, Wooyoung EricPark, JihwanKim, Min-SikKim, Jeong-GuKang, Lin-Woo
DGIST Authors
Kim, Seunghwan; Jang, Wooyoung Eric; Park, Jihwan; Kim, Min-Sik; Kim, Jeong-Gu; Kang, Lin-Woo
Issue Date
2021-06
Citation
Frontiers in Microbiology, 12, 664857
Type
Article
Author Keywords
Xoo-rice interactionsproteome and transcriptometime-resolved gene expressionXanthomonas oryzae pvoryzaepathogenicitytranslational regulation
Keywords
T3SS-DEPENDENT SECRETIONCOMPUTATIONAL PLATFORMHOMOLOGOUS EXPRESSIONBACTERIAL-BLIGHTRECOGNITION
ISSN
1664-302X
Abstract
Xanthomonas oryzae pv. oryzae (Xoo) is a plant pathogen responsible for causing bacterial blight in rice. The immediate alterations in Xoo upon initial contact with rice are essential for pathogenesis. We studied time-resolved genome-wide gene expression in pathogenicity-activated Xoo cells at the transcriptome and proteome levels. The early response genes of Xoo include genes related to cell motility, inorganic ion transport, and effectors. The alteration of gene expression is initiated as early as few minutes after the initial interaction and changes with time. The time-resolved comparison of the transcriptome and proteome shows the differences between transcriptional and translational expression peaks in many genes, although the overall expression pattern of mRNAs and proteins is conserved. The discrepancy suggests an important role of translational regulation in Xoo at the early stages of pathogenesis. The gene expression analysis using time-resolved transcriptome and proteome provides unprecedented valuable information regarding Xoo pathogenesis. © Copyright © 2021 Kim, Jang, Park, Kim, Kim and Kang.
URI
http://hdl.handle.net/20.500.11750/14007
DOI
10.3389/fmicb.2021.664857
Publisher
Frontiers Media S.A.
Related Researcher
  • Author Kim, Min-Sik Laboratory for QBIO and Precision Medicine
  • Research Interests Cancer Proteogenomics, Biomarker Discovery, Integrative Multi-Omics
Files:
Collection:
Department of New BiologyLaboratory for QBIO and Precision Medicine1. Journal Articles


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