Cited 0 time in webofscience Cited 0 time in scopus

Screening platform for assessing cellular and behavioral defects in Drosophila Melanogaster

Title
Screening platform for assessing cellular and behavioral defects in Drosophila Melanogaster
Authors
김경민정창근권민지박정향차인준조재호한명훈박성순김은선고병수이다빈정연진Lee, Sung-Bae
DGIST Authors
Lee, Sung-Bae
Issue Date
2019-06-24
Citation
제49회 한국분자세포생물학회 초파리분과 정기 학술대회
Type
Conference
Abstract
For screening drugs or molecules that can modify disease pathophysiology of human disease or conduct drug screening, the use of appropriate in vivo model with low expenditure suitable for large-scale screening is essential. Drosophila Melanogaster, whose genome contain orthologs for 75% of human disease-related genes, offers a quantitative screening platform for assessing both cellular and behavioral defects that are thought to be representative of human diseases like Parkinson’s disease(PD), Huntington’s disease(HD) or amyotrophic lateral sclerosis(ALS). Here, we present the low cost screening analysis platform available for measuring cellular and behavioral defects in Drosophila. This platform can be adapted for the use of therapeutic target discovery process as an economic and powerful in vivo screening tool for the researchers.
URI
http://hdl.handle.net/20.500.11750/14411
Publisher
한국분자세포생물학회 초파리분과
Related Researcher
  • Author Lee, Sung Bae Laboratory of Neurodegenerative Diseases and Aging
  • Research Interests Cellular mechanism of neurodegenerative diseases; Neuronal maintenance and remodeling; 퇴행성 뇌질환의 세포기전; 신경계 유지 및 리모델링 연구
Files:
There are no files associated with this item.
Collection:
Department of Brain SciencesLaboratory of Neurodegenerative Diseases and Aging2. Conference Papers


qrcode mendeley

Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.

BROWSE