Cited 0 time in
Cited 0 time in
Screening platform for assessing cellular and behavioral defects in Drosophila Melanogaster
- Title
- Screening platform for assessing cellular and behavioral defects in Drosophila Melanogaster
- Authors
- 김경민; 정창근; 권민지; 박정향; 차인준; 조재호; 한명훈; 박성순; 김은선; 고병수; 이다빈; 정연진; Lee, Sung-Bae
- DGIST Authors
- Lee, Sung-Bae
- Issue Date
- 2019-06-24
- Citation
- 제49회 한국분자세포생물학회 초파리분과 정기 학술대회
- Type
- Conference
- Abstract
- For screening drugs or molecules that can modify disease pathophysiology of human disease or conduct drug screening, the use of appropriate in vivo model with low expenditure suitable for large-scale screening is essential. Drosophila Melanogaster, whose genome contain orthologs for 75% of human disease-related genes, offers a quantitative screening platform for assessing both cellular and behavioral defects that are thought to be representative of human diseases like Parkinson’s
disease(PD), Huntington’s disease(HD) or amyotrophic lateral sclerosis(ALS). Here, we present the low cost screening analysis platform available for measuring cellular and behavioral defects in Drosophila. This platform can be adapted for the use of therapeutic target discovery process as an economic and powerful in vivo screening tool for the researchers.
- URI
- http://hdl.handle.net/20.500.11750/14411
- Publisher
- 한국분자세포생물학회 초파리분과
- Related Researcher
-
-
Lee, Sung Bae
Laboratory of Neurodegenerative Diseases and Aging
-
Research Interests
Cellular mechanism of neurodegenerative diseases; Neuronal maintenance and remodeling; 퇴행성 뇌질환의 세포기전; 신경계 유지 및 리모델링 연구
- Files:
There are no files associated with this item.
- Collection:
- Department of Brain SciencesLaboratory of Neurodegenerative Diseases and Aging2. Conference Papers
Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.