Full metadata record
| DC Field | Value | Language |
|---|---|---|
| dc.contributor.author | Son, Gowoon | - |
| dc.contributor.author | Jahanshahi, Ali | - |
| dc.contributor.author | Yoo, Seung Jun | - |
| dc.contributor.author | Boonstra, Jackson T. | - |
| dc.contributor.author | Hopkins, David A. | - |
| dc.contributor.author | Hendrik Wilhelm Maria Steinbusch | - |
| dc.contributor.author | Moon, Cheil | - |
| dc.date.accessioned | 2021-10-14T02:30:03Z | - |
| dc.date.available | 2021-10-14T02:30:03Z | - |
| dc.date.created | 2021-07-01 | - |
| dc.date.issued | 2021-06 | - |
| dc.identifier.citation | BMB Reports, v.54, no.6, pp.295 - 304 | - |
| dc.identifier.issn | 1976-6696 | - |
| dc.identifier.uri | http://hdl.handle.net/20.500.11750/15494 | - |
| dc.description.abstract | Olfactory neuropathology is a cause of olfactory loss in Alzheimer's disease (AD). Olfactory dysfunction is also associated with memory and cognitive dysfunction and is an incidental finding of AD dementia. Here we review neuropathological research on the olfactory system in AD, considering both structural and functional evidence. Experimental and clinical findings identify olfactory dysfunction as an early indicator of AD. In keeping with this, amyloid-beta production and neuroinflammation are related to underlying causes of impaired olfaction. Notably, physiological features of the spatial map in the olfactory system suggest the evidence of ongoing neurodegeneration. Our aim in this review is to examine olfactory pathology findings essential to identifying mechanisms of olfactory dysfunction in the development of AD in hopes of supporting investigations leading towards revealing potential diagnostic methods and causes of early pathogenesis in the olfactory system. | - |
| dc.language | English | - |
| dc.publisher | 생화학분자생물학회 | - |
| dc.title | Olfactory neuropathology in Alzheimer's disease: a sign of ongoing neurodegeneration | - |
| dc.type | Article | - |
| dc.identifier.doi | 10.5483/bmbrep.2021.54.6.055 | - |
| dc.identifier.wosid | 000669660700002 | - |
| dc.identifier.scopusid | 2-s2.0-85109126439 | - |
| dc.type.local | Article(Overseas) | - |
| dc.type.rims | ART | - |
| dc.description.journalClass | 1 | - |
| dc.citation.publicationname | BMB Reports | - |
| dc.identifier.kciid | ART002729234 | - |
| dc.contributor.nonIdAuthor | Son, Gowoon | - |
| dc.contributor.nonIdAuthor | Jahanshahi, Ali | - |
| dc.contributor.nonIdAuthor | Yoo, Seung Jun | - |
| dc.contributor.nonIdAuthor | Boonstra, Jackson T. | - |
| dc.contributor.nonIdAuthor | Hopkins, David A. | - |
| dc.contributor.nonIdAuthor | Hendrik Wilhelm Maria Steinbusch | - |
| dc.identifier.citationVolume | 54 | - |
| dc.identifier.citationNumber | 6 | - |
| dc.identifier.citationStartPage | 295 | - |
| dc.identifier.citationEndPage | 304 | - |
| dc.identifier.citationTitle | BMB Reports | - |
| dc.description.isOpenAccess | Y | - |
| dc.subject.keywordAuthor | Olfactory bulb | - |
| dc.subject.keywordAuthor | Olfactory dysfunction | - |
| dc.subject.keywordAuthor | Olfactory epithelium | - |
| dc.subject.keywordAuthor | Olfactory sensory neuron | - |
| dc.subject.keywordAuthor | Pathophysiology | - |
| dc.subject.keywordAuthor | Alzheimer&apos | - |
| dc.subject.keywordAuthor | s disease | - |
| dc.subject.keywordPlus | ODOR IDENTIFICATION | - |
| dc.subject.keywordPlus | SENSORY NEURONS | - |
| dc.subject.keywordPlus | AIR-FLOW | - |
| dc.subject.keywordPlus | BULB | - |
| dc.subject.keywordPlus | DYSFUNCTION | - |
| dc.subject.keywordPlus | DECLINE | - |
| dc.subject.keywordPlus | NASAL | - |
| dc.subject.keywordPlus | BRAIN | - |
| dc.subject.keywordPlus | MILD COGNITIVE IMPAIRMENT | - |
| dc.subject.keywordPlus | AMYLOID-BETA | - |
| dc.contributor.affiliatedAuthor | Son, Gowoon | - |
| dc.contributor.affiliatedAuthor | Jahanshahi, Ali | - |
| dc.contributor.affiliatedAuthor | Yoo, Seung Jun | - |
| dc.contributor.affiliatedAuthor | Boonstra, Jackson T. | - |
| dc.contributor.affiliatedAuthor | Hopkins, David A. | - |
| dc.contributor.affiliatedAuthor | Hendrik Wilhelm Maria Steinbusch | - |
| dc.contributor.affiliatedAuthor | Moon, Cheil | - |
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