Cancer Epigenetics Lab8
Overview
Epigenetic regulations are fundamental for development and maintenance of stage in post-differentiation. Because numerous genes related to development were regulated in epigenetic manner, the disorganization of epigenetic regulation can lead to uncontrolled gene expression and malignant cellular transformation. Global epigenetic changes are a hall mark of all types of cancer. My lab is interested in how epigenetic regulation is involved in tumorigenesis in the brain.
Research Summary
1. Epigenetic changes in Adult gliomas
2. Targeting childhood gliomas by interrupting epigenetic and metabolic pathways
Advisor Professor : Chung, Chan
Cancer Epigenetics Lab Homepage
Epigenetic regulations are fundamental for development and maintenance of stage in post-differentiation. Because numerous genes related to development were regulated in epigenetic manner, the disorganization of epigenetic regulation can lead to uncontrolled gene expression and malignant cellular transformation. Global epigenetic changes are a hall mark of all types of cancer. My lab is interested in how epigenetic regulation is involved in tumorigenesis in the brain.
Research Summary
1. Epigenetic changes in Adult gliomas
2. Targeting childhood gliomas by interrupting epigenetic and metabolic pathways
Advisor Professor : Chung, Chan
Cancer Epigenetics Lab Homepage
Subject
- EXPRESSION 4
- MUTATIONS 3
- PEDIATRIC HIGH-GRADE 3
- CELLS 2
- METHYLATION 2
- ACETYLATION 1
- ACTIVATION 1
- BRAIN CHOLESTEROL 1
- CANCER 1
- Cancer 1
Co-Author(s)
Related Keyword
Recent Submissions
- Therapeutic targeting of differentiation-state dependent metabolic vulnerabilities in diffuse midline glioma
- Clinical Efficacy of ONC201 in H3K27M-Mutant Diffuse Midline Gliomas Is Driven by Disruption of Integrated Metabolic and Epigenetic Pathways
- A road map for the treatment of pediatric diffuse midline glioma
- Epigenetic and Metabolic Changes in Diffuse Intrinsic Pontine Glioma
- Targeting SWI/SNF ATPases in H3.3K27M diffuse intrinsic pontine gliomas
