Title

The role of the lateral habenula in visual threat-evoked defensive behaviors

Alternative Title

시각적 위협에 의해 유발되는 방어적 행동에서의 뇌 외측고삐의 역할

DGIST Authors

Yung-Eui Kang ; Hyosang Lee ; Ja Wook Koo

Advisor

이효상

Co-Advisor(s)

Ja Wook Koo

Issued Date

2022

Awarded Date

2022/02

Citation

Yung-Eui Kang. (2022). The role of the lateral habenula in visual threat-evoked defensive behaviors. doi: 10.22677/thesis.200000593766

Type

Thesis

Subject

Defensive behaviors, looming visual stimulus, lateral habenula, escaping, freezing, chemogenetics

Description

Defensive behaviors, looming visual stimulus, lateral habenula, escaping, freezing, chemogenetics

Table Of Contents

Ⅰ. Introduction 1
Ⅱ. Materials and Methods 4
Ⅲ. Results 12
3.1 Looming visual threat activates the lateral habenula. 12
3.2 Activation of LHb neurons increases immobility of mice in response to threats. 17
3.3 Inactivation of LHb neurons increases hypermobility of mice in response to threats. 22
3.4 Vglut2+ neurons in LHb respond to looming stimuli, which evoke defensive behaviors. 28
3.5 Vglut2+ neurons in LHb promote selection of defensive behaviors in response to looming stimuli. 31
Ⅳ. Discussion 35
References 39
Summary in Korean 45

URI

http://dgist.dcollection.net/common/orgView/200000593766
http://hdl.handle.net/20.500.11750/16339

DOI

10.22677/thesis.200000593766

Degree

Master

Department

Brain and Cognitive Sciences

Publisher

DGIST

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