Defensive behaviors, looming visual stimulus, lateral habenula, escaping, freezing, chemogenetics
Table Of Contents
Ⅰ. Introduction 1 Ⅱ. Materials and Methods 4 Ⅲ. Results 12 3.1 Looming visual threat activates the lateral habenula. 12 3.2 Activation of LHb neurons increases immobility of mice in response to threats. 17 3.3 Inactivation of LHb neurons increases hypermobility of mice in response to threats. 22 3.4 Vglut2+ neurons in LHb respond to looming stimuli, which evoke defensive behaviors. 28 3.5 Vglut2+ neurons in LHb promote selection of defensive behaviors in response to looming stimuli. 31 Ⅳ. Discussion 35 References 39 Summary in Korean 45