Title

Lactobacillus reuteri ATG-F4 promotes stress-resilience through 5-HT-related signaling

Alternative Title

Lactobacills reuteri ATG-F4의 항우울 효과에 대한 행동학적 분석과 세로토닌성 기여에 대한 연구

DGIST Authors

Jiyun Lee ; Yong-Seok Oh ; Ja Wook Koo

Advisor

오용석

Co-Advisor(s)

Ja Wook Koo

Issued Date

2022

Awarded Date

2022/08

Citation

Jiyun Lee. (2022). Lactobacillus reuteri ATG-F4 promotes stress-resilience through 5-HT-related signaling. doi: 10.22677/thesis.200000627111

Type

Thesis

Subject

depression, chronic unpredictable stress, microbiota-gut-brain axis, Lactobacillus reuteri ATG-F4, serotonin

Description

depression, chronic unpredictable stress, microbiota-gut-brain axis, Lactobacillus reuteri ATG-F4, serotonin

Abstract

Table Of Contents

I. INTRODUCTION 1
II. METHODS AND MATERIALS 4
III. RESULTS 12
3.1. Antidepressant-like effect of Lactobacillus reuteri ATG-F4 in CUS-induced depressive-like behaviors 12
3.2. Modulation of caecal microbiota by F4 13
3.3. Effect of F4 on 5-HT and 5-HIAA expression levels in serum and the brain 14
3.4. Effect of F4 on 5-HT receptor mRNA expression in the mPFC 14
IV. DISCUSSION 16
V. REFERENCES 38
요 약 문 45

URI

http://dgist.dcollection.net/common/orgView/200000627111
http://hdl.handle.net/20.500.11750/16767

DOI

10.22677/thesis.200000627111

Degree

Master

Department

Department of Brain Sciences

Publisher

DGIST

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