Ⅰ. Introduction 1 1.1 Background of the study 1 1.2 Trends of the previous study 1 1.3 Necessity of this study 4 1.4 Aim and scope of this study 5 II. Theoretical & Mathematical Development 5 2.1 Wave separation method 5 2.2 Analysis of the reflected wave characteristics 7 III. Experimental Method & Materials 8 3.1 Cardio-vascular simulator 8 3.1.1 Pulse generator part 9 3.1.2 Artificial vascular part 10 3.1.3 Distal part 12 3.1.4 Measurement part 13 3.2 Verification of the wave separation system 13 3.2.1 Comparison between PWV measurement methods 13 3.2.2 Comparison of PWV according to changes in vascular elastic modulus 14 3.3 The effect of the mother branch’s characteristics 15 3.3.1 Characteristic of the resistance 16 3.3.2 Characteristic of the compliance 17 3.4 The effect of the daughter branch’s characteristics 17 3.4.1 The comparison between the mother branch and daughter branch’s characteristics 18 3.4.2 The position of daughter branch 19 3.4.3 The number of daughter branch 20 IV. Results & Discussion 21 4.1 Verification of the wave separation system 21 4.1.1 Comparison between PWV measurement methods 21 4.1.2 Comparison of PWV according to changes in vascular elastic modulus 23 4.2 The effect of the mother branch’s characteristics 24 4.2.1 Characteristic of the resistance 24 4.2.2 Characteristic of the compliance 26 4.3 The effect of the daughter branch 28 4.3.1 Comparison with mother branch 28 4.3.2 The position of daughter branch 31 4.3.3 The number of daughter branch 33 V. Conclusion 35 VI. References 36 VII. Summary 41