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dc.contributor.advisor 최홍수 -
dc.contributor.author Sooil Kim -
dc.date.accessioned 2022-08-17T16:00:12Z -
dc.date.available 2022-08-17T16:00:12Z -
dc.date.issued 2022 -
dc.identifier.uri http://dgist.dcollection.net/common/orgView/200000629984 en_US
dc.identifier.uri http://hdl.handle.net/20.500.11750/16795 -
dc.description Microrobot, Magnetic actuation, Targeted drug delivery, Biodegradation, Con-trollable drug release -
dc.description.abstract -
dc.description.statementofresponsibility N -
dc.description.tableofcontents Ⅰ. INTRODUCTION 1
1.1 Microrobots for Minimally Invasive Cancer Therapy 1
1.1.1 Traditional methods of cancer therapy 1
1.1.2 Microrobots and actuation mechanisms 4
1.1.3 Magnetic actuation 9
1.1.4 Removal of microrobots after surgery 13
1.2 Research Trends 14
1.2.1 Drug delivery microrobots 14
1.2.2 Biocompatible and biodegradable microrobots 17
1.3 Objective of this Research 25
Ⅱ. MATERIALS AND FABRICATION 28
2.1 The SugarBot Materials 28
2.2 Fabrication of SugarBot 31
2.2.1 Sucrose composite fabrication 31
2.2.2 Sugar composite gelatin-coating process 33
Ⅲ. RESULTS AND DISCUSSION 35
3.1 Characterization of the Fabricated Gelatin-Coated SugarBot 35
3.1.1 Optimization of SugarBot fabrication 35
3.1.2 Biodegradability of SugarBot 39
3.1.3 Induction heating of SugarBot 42
3.1.4 Drug loading capacity of SugarBot 44
3.2 Magnetic Manipulation of SugarBot 45
3.3 Controlled Degradation of SugarBot 50
3.4 SugarBot In-Vitro Cell Viability Test 52
Ⅳ. CONCLUSION AND FUTURE WORK 59
4.1 Conclusions 59
4.2 Future Work 61
REFERENCES 63
요약문 73
Appendix 75
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dc.format.extent 76 -
dc.language eng -
dc.publisher DGIST -
dc.subject Microrobot, Magnetic actuation, Targeted drug delivery, Biodegradation, Con-trollable drug release -
dc.title Gelatin coated biodegradable microrobot using sucrose for active drug delivery by local heating -
dc.title.alternative 국소 영역 가열을 통한 능동 약물 전달이 가능하도록 젤라틴이 코팅된 슈크로스 기반의 생분해성 마이크로로봇 -
dc.type Thesis -
dc.identifier.doi 10.22677/thesis.200000629984 -
dc.description.degree Master -
dc.contributor.department Department of Robotics and Mechatronics Engineering -
dc.contributor.coadvisor Jin-young Kim -
dc.date.awarded 2022/08 -
dc.publisher.location Daegu -
dc.description.database dCollection -
dc.citation XT.RM 김56 202208 -
dc.date.accepted 8/11/22 -
dc.contributor.alternativeDepartment 로봇및기계전자공학과 -
dc.embargo.liftdate 2027-08-31 -
dc.contributor.affiliatedAuthor Sooil Kim -
dc.contributor.affiliatedAuthor Hongsoo Choi -
dc.contributor.affiliatedAuthor Jin-young Kim -
dc.contributor.alternativeName 김수일 -
dc.contributor.alternativeName Hongsoo Choi -
dc.contributor.alternativeName 김진영 -
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