Full metadata record
| DC Field | Value | Language |
|---|---|---|
| dc.contributor.advisor | 최한경 | - |
| dc.contributor.author | Jiyoung Lee | - |
| dc.date.accessioned | 2022-08-17T16:00:14Z | - |
| dc.date.available | 2022-08-17T16:00:14Z | - |
| dc.date.issued | 2022 | - |
| dc.identifier.uri | http://dgist.dcollection.net/common/orgView/200000630783 | en_US |
| dc.identifier.uri | http://hdl.handle.net/20.500.11750/16802 | - |
| dc.description | Lateral habenula, Astrocyte, PLCη1, Depression | - |
| dc.description.abstract | - | |
| dc.description.statementofresponsibility | N | - |
| dc.description.tableofcontents | I. Introduction 1 II. Materials and Methods 7 III. Results 20 3.1 Deletion of PLCη1 in lateral habenula astrocyte with adeno-associated viral vector 20 3.2 PLCη1 in lateral habenula effect on depressive-like behavior 23 3.3 PLCη1 in lateral habenula did not effect the motor function and anxiety-like behavior 26 3.4 PLCη1 in lateral habenula did not alter working and fear memory 30 3.5 Deletion of astrocytic PLCη1disrupts tonic glutamate current in the LHb while sparing tonic GABA current 33 3.6 Impairment of extra synaptic long-term depression (LTD) in the deletion mice of astrocytic PLCη1 36 3.7 Astrocytic PLCη1 in lateral habenula disrupt synaptic function and regulate mood state 40 IV. Discussion 42 V. References 45 |
- |
| dc.format.extent | 50 | - |
| dc.language | eng | - |
| dc.publisher | DGIST | - |
| dc.subject | Lateral habenula, Astrocyte, PLCη1, Depression | - |
| dc.title | Deletion of Phospholipase C eta 1 in habenula astrocyte induces depressive behavior | - |
| dc.type | Thesis | - |
| dc.identifier.doi | 10.22677/thesis.200000630783 | - |
| dc.description.degree | Master | - |
| dc.contributor.department | Department of Brain Sciences | - |
| dc.contributor.coadvisor | Jeongyeon Kim | - |
| dc.date.awarded | 2022/08 | - |
| dc.publisher.location | Daegu | - |
| dc.description.database | dCollection | - |
| dc.citation | XT.BM 이786 202208 | - |
| dc.date.accepted | 8/11/22 | - |
| dc.contributor.alternativeDepartment | 뇌과학과 | - |
| dc.embargo.liftdate | 2024-02-28 | - |
| dc.contributor.affiliatedAuthor | Jiyoung Lee | - |
| dc.contributor.affiliatedAuthor | Han Kyoung Choe | - |
| dc.contributor.affiliatedAuthor | Jeongyeon Kim | - |
| dc.contributor.alternativeName | 이지영 | - |
| dc.contributor.alternativeName | Han Kyoung Choe | - |
| dc.contributor.alternativeName | 김정연 | - |
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