Full metadata record
DC Field | Value | Language |
---|---|---|
dc.contributor.author | Kim, Min Jung | - |
dc.contributor.author | Lim, Heejin | - |
dc.contributor.author | Kim, Muwoong | - |
dc.contributor.author | Choi, Yuri | - |
dc.contributor.author | Nguyen, Thy Ngoc Chau | - |
dc.contributor.author | Park, Seung Cheol | - |
dc.contributor.author | Kim, Kwang Pyo | - |
dc.contributor.author | Jung, Junyang | - |
dc.contributor.author | Kim, Min-Sik | - |
dc.date.accessioned | 2023-01-09T17:10:16Z | - |
dc.date.available | 2023-01-09T17:10:16Z | - |
dc.date.created | 2022-07-06 | - |
dc.date.issued | 2022-06 | - |
dc.identifier.issn | 2233-4203 | - |
dc.identifier.uri | http://hdl.handle.net/20.500.11750/17351 | - |
dc.description.abstract | Human tissues and organs can be preserved intact by fixation with formalin for the future analysis of biomolecules of interest. With the advances in high-throughput methods, numerous protocols have been developed and optimized to attain the most pathophysiological information out of biomolecules, including RNA and proteins, in formalin-fixed samples. However, there is no systematic study to examine the effects of formalin fixation on the lipidome of biological samples in a global fashion. In this study, we conducted a mass spectrometry-based analysis to survey the alteration in the lipidome of mice brains by fixation methods. A total of 308 lipids were quantitatively measured using triple quadrupole mass spectrometry. We found that most were unchanged after formalin fixation except for a few lipid classes such as phosphatidylethanolamine. © Korean Society for Mass Spectrometry. | - |
dc.language | English | - |
dc.publisher | 사단법인 한국질량분석학회 | - |
dc.title | Lipid N-formylation Occurs During Fixation with Formalin | - |
dc.type | Article | - |
dc.identifier.doi | 10.5478/MSL.2022.13.2.35 | - |
dc.identifier.scopusid | 2-s2.0-85134014649 | - |
dc.identifier.bibliographicCitation | Mass Spectrometry Letters, v.13, no.2, pp.35 - 40 | - |
dc.identifier.kciid | ART002856785 | - |
dc.description.isOpenAccess | FALSE | - |
dc.subject.keywordAuthor | formalin fixation | - |
dc.subject.keywordAuthor | N-formylation | - |
dc.subject.keywordAuthor | mass spectrometry-based lipidomics | - |
dc.subject.keywordPlus | MASS-SPECTROMETRY | - |
dc.subject.keywordPlus | DNA | - |
dc.citation.endPage | 40 | - |
dc.citation.number | 2 | - |
dc.citation.startPage | 35 | - |
dc.citation.title | Mass Spectrometry Letters | - |
dc.citation.volume | 13 | - |
There are no files associated with this item.