Cited 4 time in webofscience Cited 5 time in scopus

Brain metabolism as a modulator of autophagy in neurodegeneration

Title
Brain metabolism as a modulator of autophagy in neurodegeneration
Authors
Lim, Y[Lim, Yun]Cho, H[Cho, Hanchae]Kim, EK[Kim, Eun-Kyoung]
DGIST Authors
Lim, Y[Lim, Yun]; Cho, H[Cho, Hanchae]; Kim, EK[Kim, Eun-Kyoung]
Issue Date
2016-10-15
Citation
Brain Research, 1649, 158-165
Type
Article
Article Type
Review
Keywords
AutophagyBrainHormoneMetabolismNeurodegenerative DiseaseNutrient
ISSN
0006-8993
Abstract
Emerging evidence that autophagy serves as a sweeper for toxic materials in the brain gives us new insight into the pathophysiology of neurodegenerative diseases. Autophagy is important for maintaining cellular homeostasis associated with metabolism. Some neurodegenerative diseases such as Alzheimer׳s and Parkinson׳s diseases are accompanied by altered metabolism and autophagy in the brain. In this review, we discuss how hormones and nutrients regulate autophagy in the brain and affect neurodegeneration. This article is part of a Special Issue entitled SI:Autophagy. © 2016 Elsevier B.V.
URI
http://hdl.handle.net/20.500.11750/2173
DOI
10.1016/j.brainres.2016.02.049
Publisher
Elsevier B.V.
Related Researcher
  • Author Kim, Eun Kyoung Lab of Neuro-Metabolism & Neurometabolomic Research Center
  • Research Interests Neural functions in metabolic diseases; 뇌신경세포와 비만; 당뇨 등의 대사 질환 관련 연구
Files:
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Collection:
Department of Brain and Cognitive SciencesLab of Neuro-Metabolism & Neurometabolomic Research Center1. Journal Articles


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