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Micromagnet Conductors for High-Resolution Separation of Magnetically Driven Beads and Cells at Multiple Frequencies

Title
Micromagnet Conductors for High-Resolution Separation of Magnetically Driven Beads and Cells at Multiple Frequencies
Authors
Hu, X[Hu, Xinghao]Torati, SR[Torati, Sri Ramulu]Shawl, AI[Shawl, Asif Iqbal]Lim, B[Lim, Byeonghwa]Kim, K[Kim, Kunwoo]Kim, C[Kim, CheolGi]
DGIST Authors
Torati, SR[Torati, Sri Ramulu]; Shawl, AI[Shawl, Asif Iqbal]; Lim, B[Lim, Byeonghwa]; Kim, K[Kim, Kunwoo]; Kim, C[Kim, CheolGi]
Issue Date
2016
Citation
IEEE Magnetics Letters, 7
Type
Article
Article Type
Article
Keywords
BiomagneticsCellsCritical FrequenciesDragHigh-Resolution SeparationsIn-Plane Rotating FieldMagnetic SusceptibilityMagnetismMulti-FrequenciesMulti FrequencyRotating DisksRotating FieldsRotating Magnetic FieldsSelective SeparationSeparationSuperparamagnetic BeadsSuperparamagnetism
ISSN
1949-307X
Abstract
We demonstrate a separation method for complex mixture of superparamagnetic beads using half-disk pathways, under an in-plane rotating magnetic field, which is highly sensitive to the bead size and magnetic susceptibility. The non-linear dynamics of the beads moving along the half-disk pathways at multiple frequencies can be divided into three regimes: a phase-locked regime at low driving frequencies, a phase-slipping regime above the first critical frequency fc1, and a phase-insulated regime above the second critical frequency fc2 in which the beads just hop at the gaps between two half-disks. Hence, based on the dynamical motions, the beads with varied sizes or heterogenic magnetic properties can be separated efficiently. Furthermore, a bio-selective separation of bead plus human monocytic leukemia (THP-1) cell complexes from bare beads has been achieved due to the increased drag force on the complexes, resulting in a decreased critical frequency. © 2010-2012 IEEE.
URI
http://hdl.handle.net/20.500.11750/2776
DOI
10.1109/LMAG.2016.2614253
Publisher
Institute of Electrical and Electronics Engineers Inc.
Related Researcher
  • Author Kim, CheolGi Lab for NanoBio-MatErials & SpinTronics(nBEST)
  • Research Interests Magnetic Materials and Spintronics; Converging Technology of Nanomaterials and Biomaterials; Bio-NEMS;MEMS
Files:
There are no files associated with this item.
Collection:
Department of Emerging Materials ScienceETC1. Journal Articles
Department of Emerging Materials ScienceLab for NanoBio-Materials & SpinTronics(nBEST)1. Journal Articles


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