Department of Energy Science and Engineering
Electrochemistry Laboratory for Sustainable Energy(ELSE)
1. Journal Articles
Non-Cross-Bridged Tetraazamacrocyclic Chelator for Stable Cu-64-Based Radiopharmaceuticals
- Title
- Non-Cross-Bridged Tetraazamacrocyclic Chelator for Stable Cu-64-Based Radiopharmaceuticals
- Author(s)
- Dale, AV[Dale, Ajit V.] ; Pandya, DN[Pandya, Darpan N.] ; Kim, JY[Kim, Jung Young] ; Lee, H[Lee, Hochun] ; Ha, YS[Ha, Yeong Su] ; Bhatt, N[Bhatt, Nikunj] ; Kim, J[Kim, Jonghee] ; Seo, JJ[Seo, Jeong Ju] ; Lee, W[Lee, Woonghee] ; Kim, SH[Kim, Sung Hong] ; Yoon, YR[Yoon, Young-Ran] ; An, GI[An, Gwang Il] ; Yoo, J[Yoo, Jeongsoo]
- DGIST Authors
- Lee, H[Lee, Hochun]
- Issued Date
- 2013-10
- Type
- Article
- Article Type
- Article
- Subject
- Bi-Functional Chelator ; Copper 64 ; Copper Complex ; Imaging Agent ; Isotope Labeling ; Macrocyclic Compound ; Priority Journal ; Radiopharmaceutical
- ISSN
- 1948-5875
- Abstract
- N-mono/dimethylated TE2A tetraazamacrocycles (MM-TE2A and DM-TE2A) were synthesized in high yields. Both Cu-MM/DM-TE2A complexes showed increased kinetic stability compared to that of Cu-TE2A, whereas Cu-DM-TE2A showed even higher in vitro stability than that of Cu-ECB-TE2A. MM-TE2A and DM-TE2A were quantitatively radiolabeled with 64Cu ions and showed rapid clearance from the body to emerge as a potential efficient bifunctional chelator. © 2013 American Chemical Society.
- Publisher
- American Chemical Society
- Related Researcher
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Lee, Hochun 에너지공학과
- Research Interests Lithium-ion batteries; Novel Materials for rechargeable batteries; Novel energy conversion;storage systems; Electrochemistry; 리튬이차전지; 이차전지용 신규 전극 및 전해액; 신규 에너지변환 및 저장 시스템; 전기화학
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