A Mononuclear Non-Heme High-Spin Iron(III)-Hydroperoxo Complex as an Active Oxidant in Sulfoxidation Reactions

Abstract

We report the first direct experimental evidence showing that a high-spin iron(III)-hydroperoxo complex bearing an N-methylated cyclam ligand can oxidize thioanisoles. DFT calculations showed that the reaction pathway involves heterolytic O-O bond cleavage and that the choice of the heterolytic pathway versus the homolytic pathway is dependent on the spin state and the number of electrons in the dxz orbital of the FeIII-OOH species. © 2013 American Chemical Society.