C-Reactive protein-directed immobilization of phosphocholine ligands on a solid surface
- Title
- C-Reactive protein-directed immobilization of phosphocholine ligands on a solid surface
- Author(s)
- Kim, E[Kim, Eunjoo] ; Kim, HC[Kim, Hyun-Chul] ; Lee, SG[Lee, Se Geun] ; Lee, SJ[Lee, Sung Jun] ; Go, TJ[Go, Tae-Jung] ; Baek, CS[Baek, Chul Su] ; Jeong, SW[Jeong, Sang Won]
- DGIST Authors
- Kim, E[Kim, Eunjoo] ; Kim, HC[Kim, Hyun-Chul] ; Lee, SG[Lee, Se Geun] ; Lee, SJ[Lee, Sung Jun] ; Go, TJ[Go, Tae-Jung] ; Baek, CS[Baek, Chul Su] ; Jeong, SW[Jeong, Sang Won]
- Issued Date
- 2011
- Type
- Article
- Article Type
- Article
- Subject
- 3(4) Vinylbenzyl 12 Phosphocholine Dodecanoate ; Adsorption ; Antibodies, Immobilized ; Binding Affinity ; C-Reactive Protein ; C Reactive Protein ; Human ; Humans ; Immunoassay ; Ligand ; Ligands ; Molecular Imprinting ; Non-Human ; Oils ; Phosphorylcholine ; Polymer ; Polymerization ; Polystyrenes ; Protein Analysis ; Protein Immobilization ; Serum ; Solid ; Styrene ; Surface Properties ; Unclassified Drug ; Water
- ISSN
- 1359-7345
- Abstract
- The complexes of C-reactive protein (CRP) with its polymerizable phosphocholine ligands adsorbed at the styrene-water interface were polymerized. The molecularly imprinted polymer (MIP) exhibited a binding affinity for CRP comparable to that of immobilized anti-CRP antibody. The determination of human serum CRP using the MIP-based sandwich immunoassay has been demonstrated. © 2011 The Royal Society of Chemistry.
- Publisher
- Royal Society of Chemistry
- Related Researcher
-
-
Kim, Eunjoo 전자정보시스템연구부
- Research Interests Biomarker; liquid biopsy; molecular diagnosis; nanobiosensor; drug delivery; exosome
-
- Files in This Item:
-
There are no files associated with this item.
- Appears in Collections:
- Magnet-Controlled Materials Research Group 1. Journal Articles
Items in Repository are protected by copyright, with all rights reserved, unless otherwise indicated.