Amperometric acetylcholine biosensor based on chitosan porous structure
- Title
- Amperometric acetylcholine biosensor based on chitosan porous structure
- Alternative Title
- 키토산 포러스 구조에 기반한 아세틸콜린 센서 제작
- Author(s)
- Jieun Son
- DGIST Authors
- Jieun Son ; Kyung-In Jang ; Sung-Won Lee
- Advisor
- 장경인
- Co-Advisor(s)
- Sung-Won Lee
- Issued Date
- 2023
- Awarded Date
- 2023-02-01
- Type
- Thesis
- Description
- Closed-loop system, Alzheimer’s disease, Acetylcholine sensor, Chitosan, Porous structure
- Table Of Contents
-
Ⅰ. Introduction 1
ⅠI. Backgrounds 3
2.1 Closed-loop Neuromodulation System 3
2.2 Acetylcholine Metabolism 4
2.3 Previous drug treatment study of Alzheimer Disease 5
2.4 Neurotransmitters 6
ⅠII. Materials and Methods 7
3.1 Reagents 7
3.2 Apparatus 7
3.3 Preparation of Chitosan solution 7
3.4 Fabrication of Acetylcholine sensor 8
ⅠV. Results and Discussion 10
4.1 Characteristics of Chitosan porous structure 10
4.1.1 Pore distribution 11
4.2 In-vitro Test 12
4.2.1 Cyclic Voltammetry (CV) 12
4.2.2 Chronoamperometry (CA) 13
4.2.3 Linearity 14
4.2.4 Stability 15
4.2.5 Selectivity 15
4.3 Fourier transform infrared (FTIR) 16
4.4 Chitosan damage in the Brain 17
V. Conclusion 18
References 19
요 약 문 21
- URI
-
http://hdl.handle.net/20.500.11750/45715
http://dgist.dcollection.net/common/orgView/200000653195
- Degree
- Master
- Publisher
- DGIST
- Related Researcher
-
-
Jang, Kyung-In
- Research Interests Extreme mechanics; Stand-alone electronics; Heterogeneous materials; Biocompatible interfaces
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- Files in This Item:
-
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- Appears in Collections:
- Department of Robotics and Mechatronics Engineering Theses Master
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