Full metadata record
DC Field | Value | Language |
---|---|---|
dc.contributor.author | Lee, Joo Young | - |
dc.contributor.author | Kim, Jin Young | - |
dc.contributor.author | Kim, Bom-Taeck | - |
dc.contributor.author | Koo, JaeHyung | - |
dc.contributor.author | Lee, Jong-Ho | - |
dc.contributor.author | Jahng, Jeong Won | - |
dc.date.accessioned | 2023-06-09T10:40:17Z | - |
dc.date.available | 2023-06-09T10:40:17Z | - |
dc.date.created | 2018-03-29 | - |
dc.date.issued | 2014 | - |
dc.identifier.issn | 0039-7660 | - |
dc.identifier.uri | http://hdl.handle.net/20.500.11750/45967 | - |
dc.description.abstract | This study was conducted to examine if ?-amino butyric acid (GABA)-ergic neurotransmission is implicated in the regulation of stress-induced feeding. Rats received GABAA receptor antagonist bicuculline before each stress session during 10 days of daily restraint stress. The hypothalamic mRNA expression of corticotropin-releasing hormone (CRH) and neuropeptide Y (NPY) was analyzed by in situ hybridization, and the plasma corticosterone with radioimmunoassay. Bicuculline ameliorated the decrease in food intake by repeated restraints, but not by a single restraint. Corticosterone increase responding to acute stress, but not to repeated restraints, was attenuated by bicuculline. Stress-induced CRH expression was blunted by bicuculline pre-treatment. Restraint stress did not affect NPY expression, regardless of bicuculline pre-treatment. It is concluded that GABAA receptors may mediate chronic, but not acute, stress-induced suppression in food intake, possibly in relation with anorectic action of the hypothalamic CRH, and the hypothalamic NPY may not be implicated in its regulatory mechanism. | - |
dc.language | English | - |
dc.publisher | Polish Forestry Society | - |
dc.title | Bicuculline ameliorated chronic, but not acute, stress-induced feeding suppression | - |
dc.type | Article | - |
dc.identifier.bibliographicCitation | Sylwan, pp.312 - 347 | - |
dc.description.isOpenAccess | FALSE | - |
dc.subject.keywordAuthor | Corticosterone | - |
dc.subject.keywordAuthor | Food intake | - |
dc.subject.keywordAuthor | Stress | - |
dc.subject.keywordAuthor | γ-amino butyric acid | - |
dc.subject.keywordPlus | BODY-WEIGHT | - |
dc.subject.keywordPlus | RAT-BRAIN | - |
dc.subject.keywordPlus | GABA(A) RECEPTORS | - |
dc.subject.keywordPlus | RESTRAINT STRESS | - |
dc.subject.keywordPlus | ARCUATE NUCLEUS | - |
dc.subject.keywordPlus | NEONATAL MATERNAL SEPARATION | - |
dc.subject.keywordPlus | NPY MESSENGER-RNA | - |
dc.subject.keywordPlus | FOOD-INTAKE | - |
dc.subject.keywordPlus | NEUROPEPTIDE-Y | - |
dc.subject.keywordPlus | ENERGY-BALANCE | - |
dc.identifier.url | https://sylwan.ibles.org/syl/search.php?searchQuery=Joo%20Young%20Lee,%20Jin%20Young%20Kim,%20Bom-Taeck%20Kim,%20JaeHyung%20Koo,%20Jong-Ho%20Lee,%20Jeong%20Won%20Jahng\n\n1.%20Department%20of%20Oral%20and%20Maxillofacial%20Surgery,%20Dental%20Research%20Institute,%20Seoul%20National%20University%20School%20of%20Dentistry,%20Seoul,%20Korea;%202.%20Department%20of%20Family%20Pra&search=search | - |
dc.citation.endPage | 347 | - |
dc.citation.startPage | 312 | - |
dc.citation.title | Sylwan | - |
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