In vivo high-resolution flexible electrode array for multi-site recording and stimulation

Abstract

The Neural Interface systems for brain disease treatment, brain function research, and brain‐machine interface (BMI) implementation has focused on non‐invasive methods so far, but has a limitation in that it has a low resolution. The purpose of this study is to develop a flexible, high‐resolution Neural Interface systems with biocompatibility and mechanical properties to overcome the limitations of the conventional brain interface electrodes, and to improve long‐term use suitability for practical clinical use. In this study, we measured brain signals or stimulated neuronal cells to treat brain disorders and for brain research using non‐human primate. A minimal invasive hybrid electrocorticography (ECoG) electrode arrays was used without damaging the brain. These ECoG electrodes can be used to measure local field potential (LFP) across large areas of the brain. In this study, we present the results of in‐vivo recording and stimulation of the brain using the developed electrode array.