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Enhancement of Perivascular Spaces in 7 T MR Image using Haar Transform of Non-local Cubes and Block-matching Filtering
- Enhancement of Perivascular Spaces in 7 T MR Image using Haar Transform of Non-local Cubes and Block-matching Filtering
- Hou, Yingkun; Park, Sang Hyun; Wang, Qian; Zhang, Jun; Zong, Xiaopeng; Lin, Weili; Shen, Dinggang
- DGIST Authors
- Park, Sang Hyun
- Issue Date
- Scientific Reports, 7(1)
- Article Type
- Perivascular spaces (PVSs) in brain have a close relationship with typical neurological diseases. The quantitative studies of PVSs are meaningful but usually difficult, due to their thin and weak signals and also background noise in the 7 T brain magnetic resonance images (MRI). To clearly distinguish the PVSs in the 7 T MRI, we propose a novel PVS enhancement method based on the Haar transform of non-local cubes. Specifically, we extract a certain number of cubes from a small neighbor to form a cube group, and then perform Haar transform on each cube group. The Haar transform coefficients are processed using a nonlinear function to amplify the weak signals relevant to the PVSs and to suppress the noise. The enhanced image is reconstructed using the inverse Haar transform of the processed coefficients. Finally, we perform a block-matching 4D filtering on the enhanced image to further remove any remaining noise, and thus obtain an enhanced and denoised 7 T MRI for PVS segmentation. We apply two existing methods to complete PVS segmentation, i.e., (1) vesselness-Thresholding and (2) random forest classification. The experimental results show that the PVS segmentation performances can be significantly improved by using the enhanced and denoised 7 T MRI. © 2017 The Author(s).
- Nature Publishing Group
- Related Researcher
Park, Sang Hyun
Medical Image & Signal Processing Lab
컴퓨터비전, 인공지능, 의료영상처리
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- Department of Robotics EngineeringMedical Image & Signal Processing Lab1. Journal Articles
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