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Physiological dopamine-spiking dynamics in uncertain reward conditions

Title
Physiological dopamine-spiking dynamics in uncertain reward conditions
Alternative Title
불확실한 보상 조건에서의 생리적 도파민 신경 활성 역학
Author(s)
Minji Kim
DGIST Authors
Minji KimKwang LeeHyosang Lee
Advisor
이광
Co-Advisor(s)
Hyosang Lee
Issued Date
2025
Awarded Date
2025-02-01
Type
Thesis
Description
Dopamine signaling, Neural firing, Uncertain conditions, Different reward probabilities, An integrated opto-probe device
Table Of Contents
Ⅰ. Introduction 1

Ⅱ. Methods 3
2.1 Animal 3
2.2 Surgical procedures 3
2.3 Behavioral task 3
2.4 Electrophysiology 4
2.5 Fiber photometry 6
2.6 Immunohistochemistry 6
2.7 Quantification and statistical analysis 7

Ⅲ. Results 9
3.1 Behavioral changes in response to different reward probabilities in a Pavlovian conditioning task 9
3.2 Classification and analysis of spiking activity in the ventral striatum 14
3.3 Influence of dopamine response and neural activation under probabilistic reward conditions 17

Ⅳ. Discussion 24

Ⅴ. Reference 26

Abstract in Korean 30
URI
http://hdl.handle.net/20.500.11750/58007
http://dgist.dcollection.net/common/orgView/200000828401
DOI
10.22677/THESIS.200000828401
Degree
Master
Department
Department of Brain Sciences
Publisher
DGIST
Related Researcher
  • 이광 Lee, Kwang
  • Research Interests 신경회로; 신경기록; 신경조절; 신경 모델링; 뇌-기계 인터페이스
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Department of Brain Sciences Theses Master

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