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  Department of Robotics and Mechatronics Engineering Theses Ph.D.

A Unified Framework for Vascular Imaging Enhancement in Ultrasound and Photoacoustics

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dc.contributor.advisor 유재석 -
dc.contributor.author Guezzi Nizar -
dc.date.accessioned 2026-01-23T10:53:58Z -
dc.date.available 2026-01-23T10:53:58Z -
dc.date.issued 2026 -
dc.identifier.uri https://scholar.dgist.ac.kr/handle/20.500.11750/59604 -
dc.identifier.uri http://dgist.dcollection.net/common/orgView/200000943273 -
dc.description Signal Processing, Image Processing, Image reconstruction -
dc.description.tableofcontents LIST OF CONTENTS
ABSTRACT i
LIST OF CONTENTS iv
LIST OF TABLES viii
LIST OF FIGURES viii
1. Introduction 1
1.1 Background and Motivation 1
1.2 Challenges in Vascular Imaging 3
1.2.1 Hardware Complexity and Safety in 3D Ultrasound 3
1.2.2 Clutter and Beamforming Limitations in Doppler Ultrasound 4
1.2.3 Noise and Energy Constraints in Photoacoustic Microscopy 5
1.2.4 General Trade-offs in Vascular Imaging 6
1.3 State of the Art 7
1.3.1 Three-Dimensional Ultrasound with Row-Column Arrays 7
1.3.2 Advanced Beamformers in Ultrafast Doppler Imaging 8
1.3.3 Post-Processing in Photoacoustic Microscopy 9
1.3.4 Summary of the State of the Art 10
1.4 Vascular Enhancement Across the Imaging Chain 11
1.4.1 Transmit Optimization 11
1.4.2 Reconstruction 11
1.4.3 Post-Processing 12
1.5 Contributions of This Thesis 13
1.5.1 Transmit-Level Enhancement in 3D Ultrasound with RCA Arrays 13

1.5.2 Reconstruction-Level Enhancement with Dual-Stage Coherence Beamforming 14
1.5.3 Post-Processing Enhancement in Photoacoustic Microscopy 15
1.5.4 Summary of Contributions. 15
1.6 Thesis Outline 16
2. Transmit Level Vascular Enhancement in 3D Ultrasound with Row-Column Arrays 19
2.1 Introduction 20
2.2 Methods 24
2.2.1 Transmission scheme 24
2.2.2 Coded excitation and pulse decoding 25
2.2.3 Optimization of transmission parameters 28
2.2.4 Data acquisition 29
2.2.5 Image reconstruction scheme 30
2.3 Results 32
2.3.1 Image spatial resolution evaluation 32
2.3.2 Optimized transmission parameters 33
2.3.3 Axial resolution and sidelobe level 35
2.3.5 Increased penetration depth 36
2.3.6 In vivo results 38
2.4 Discussion 40
2.5 Conclusion 43
2.6 Acknowledgement 43
3. Reconstruction-Level Vascular Enhancement with Dual-Stage Coherence Beamforming 44
3.1 Introduction 45
3.2 Methods 47

3.2.1 DAS and CF beamformers 47
3.2.2 Dual stage coherence beamformer 49
3.2.2 Simulation and experimental setup 51
3.2.3 Signal processing pipeline 52
3.3 Results 53
3.3.1 Point spread function (PSF) analysis 53
3.3.2 Three target scenario 54
3.3.3 Noise floor estimation in multi-target scenarios 55
3.3.4 In-vivo rat brain data (single frame analysis) 56
3.3.5 In-vivo rat brain data (power doppler imaging) 58
3.3.6 In-vivo rat brain data (directional power doppler ) 59
3.4 Discussion 61
3.5 Conclusion 63
3.6 Acknowledgement 63
4. Post-Processing Level Vascular Enhancement in Photoacoustic Microscopy 64
4.1 Introduction 64
4.2 Methods 66
4.2.1 Optical-resolution photoacoustic microscopy 66
4.2.2 Animal preparation 68
4.2.3 Image pre-processing 68
4.2.4 Image post-processing 69
4.3 Results and discussion 73
4.3.1 Phantom experiment results 73
4.3.2 In vivo experiment results 75

4.4 Conclusion 81
4.5 Acknowledgment 81
5. A Unified Framework for Vascular Imaging Enhancement: An Ultrasound Case Study 82
5.1 Introduction 82
5.2 Methods 83
5.3 Results 84
5.4 Discussion and Conclusion 87
6. Conclusion and Perspectives 89
6.1 Conclusion 89
6.2 Perspectives 93
Acknowledgments 95
List of achievements 96
Journal publications (first authored papers) 96
Conferences 97
References 98
초음파 및 광음향 영상에서 혈관 영상 향상을 위한 통합 프레임워크 116
요 약 문 116		 -
dc.format.extent 117 -
dc.language eng -
dc.publisher DGIST -
dc.title A Unified Framework for Vascular Imaging Enhancement in Ultrasound and Photoacoustics -
dc.type Thesis -
dc.identifier.doi 10.22677/THESIS.200000943273 -
dc.description.degree Doctor -
dc.contributor.department Department of Robotics and Mechatronics Engineering -
dc.contributor.coadvisor Hoejoon Kim -
dc.date.awarded 2026-02-01 -
dc.publisher.location Daegu -
dc.description.database dCollection -
dc.citation XT.RD G939 202602 -
dc.date.accepted 2026-01-19 -
dc.contributor.alternativeDepartment 로봇및기계전자공학과 -
dc.subject.keyword Signal Processing, Image Processing, Image reconstruction -
dc.contributor.affiliatedAuthor Guezzi Nizar -
dc.contributor.affiliatedAuthor Jaesok Yu -
dc.contributor.affiliatedAuthor Hoejoon Kim -
dc.contributor.alternativeName Nizar Guezzi -
dc.contributor.alternativeName Jaesok Yu -
dc.contributor.alternativeName 김회준 -
dc.rights.embargoReleaseDate 2030-02-28 -
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