Title

Characterization of CBP-mediated non-cell-autonomous Control of Dendritic Arborization by Glia

DGIST Authors

Seung Yeon Kim ; Sung Bae Lee

Advisor

이성배

Issued Date

2026

Awarded Date

2026-08-01

Type

Thesis

Description

Glia, dCBP, Dendritic arbor, non-cell-autonomous, Drosophila

Table Of Contents

List of Contents
Abstract i
List of contents ii
List of figures iii

I. INTRODUCTION 1
II. MATERIALS AND METHODS 4
III. RESULTS
3.1 The knockdown of glial dCBP led to increased terminal dendritic branch length in neighboring C4da neurons 8
3.2 Reduced histone acetyltransferase activity of dCBP by knockdown in glia modifies terminal dendritic branch length in C4da neurons 9
3.3 Disruption of the glial secretory pathway is insufficient to alter neighboring dendritic morphology 11
3.4 The knockdown of dCBP in subperineurial and perineurial glia is sufficient to alter the dendritic arborization of C4da neurons 12
3.5 Alteration of dendritic arbor by glial dCBP knockdown is specific at third instar larval stage 14

IV. DISCUSSION 35
V. REFERENCES 37
VI. SUMMARY （국문요약） 39

URI

https://scholar.dgist.ac.kr/handle/20.500.11750/60759
http://dgist.dcollection.net/common/orgView/200001006814

DOI

10.22677/THESIS.200001006814

Degree

Master

Department

Department of Brain Sciences

Publisher

DGIST

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